Gene

ddx41

ID
ZDB-GENE-030131-1927
Name
DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
Symbol
ddx41 Nomenclature History
Previous Names
  • wu:fb92e02
Type
protein_coding_gene
Location
Ambiguous Mapping Details/Browsers
Description
Predicted to have ATP binding activity; carbohydrate binding activity; and nucleic acid binding activity. Involved in NIK/NF-kappaB signaling; innate immune response; and response to virus. Localizes to cytoplasm and nucleus. Is expressed in brain; digestive system; gill; heart; and immune system. Orthologous to human DDX41 (DEAD-box helicase 41).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Ma et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ddx41 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Myeloproliferative/lymphoproliferative neoplasms, familial (multiple types), susceptibility to} 616871
Associated With ddx41 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000922 D-galactoside/L-rhamnose binding SUEL lectin domain
Domain IPR011545 DEAD/DEAH box helicase domain
Domain IPR014001 Helicase superfamily 1/2, ATP-binding domain
Domain IPR014014 RNA helicase, DEAD-box type, Q motif
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR043159 D-galactoside/L-rhamnose binding SUEL lectin domain superfamily
Domain Details Per Protein
Protein Length DEAD/DEAH box helicase domain D-galactoside/L-rhamnose binding SUEL lectin domain D-galactoside/L-rhamnose binding SUEL lectin domain superfamily Helicase superfamily 1/2, ATP-binding domain P-loop containing nucleoside triphosphate hydrolase RNA helicase, DEAD-box type, Q motif
UniProtKB:Q803D3 306
UniProtKB:E9QFV1 222
UniProtKB:A0A2R8QHE6 326
UniProtKB:F1QW66 229
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-ddx41 Rabbit
  • IHC
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations