Gene

smurf2

ID
ZDB-GENE-030131-1830
Name
SMAD specific E3 ubiquitin protein ligase 2
Symbol
smurf2 Nomenclature History
Previous Names
  • wu:fb82a11
  • wu:fc41c02
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have ubiquitin protein ligase activity. Predicted to be involved in several processes, including negative regulation of BMP signaling pathway; protein polyubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to localize to cytoplasm. Orthologous to human SMURF2 (SMAD specific E3 ubiquitin protein ligase 2).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With smurf2 Human Ortholog
No data available
Associated With smurf2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000008 C2 domain
Domain IPR000569 HECT domain
Domain IPR001202 WW domain
Family IPR024928 E3 ubiquitin-protein ligase, SMURF1 type
Homologous_superfamily IPR035892 C2 domain superfamily
Homologous_superfamily IPR035983 HECT, E3 ligase catalytic domain
Homologous_superfamily IPR036020 WW domain superfamily
Domain Details Per Protein
Protein Length C2 domain C2 domain superfamily E3 ubiquitin-protein ligase, SMURF1 type HECT domain HECT, E3 ligase catalytic domain WW domain WW domain superfamily
UniProtKB:A9JRZ0 765
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations