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General Information
ZIRC
ZFIN ID: ZDB-GENE-030131-1830
Gene Name: SMAD specific E3 ubiquitin protein ligase 2
Gene Symbol: smurf2    Nomenclature History

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Previous Names: wu:fb82a11, wu:fc41c02

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have ubiquitin protein ligase activity. Predicted to be involved in several processes, including negative regulation of BMP signaling pathway; protein polyubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to localize to the cytoplasm. Orthologous to human SMURF2 (SMAD specific E3 ubiquitin protein ligase 2).
Genome Resources: Alliance (1),  Gene:563633 (1),  Ensembl(GRCz11):ENSDARG00000038067 (2)
GENE EXPRESSION
Curated Microarray Expression: GEO (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH smurf2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH smurf2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process ubiquitin-dependent protein catabolic process (more)
Cellular Component cytoplasm (more)
Molecular Function transferase activity (more)
GO Terms (all 15)
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA smurf2-201 (1)    Ensembl 3399
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM smurf2 No data available
MARKER RELATIONSHIPS
smurf2 Contained in: [BAC] DKEY-226A5 (1) (order this)
smurf2 Encodes: [EST] fb82a11, fc41c02
[cDNA] MGC:175218 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001114426 (1) 3443 bp
Genomic GenBank:BX085195 (1) 227111 bp Blast at MegaBLAST
Polypeptide UniProtKB:A9JRZ0 (1) 765 aa
Sequence Clusters UniGene:77630 (1)
Sequence Information (all 15)
ORTHOLOGY for smurf2 ( Chr: 3 )
CITATIONS (26)