ZFIN ID: ZDB-GENE-030131-179
Gene Name: IST1 factor associated with ESCRT-III
Gene Symbol: ist1    Nomenclature History

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Previous Names: fb16b04, wu:fb16b04, wu:fi89e07, zgc:55671

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Involved in axon extension and endosome organization. Is expressed in female organism. Orthologous to human IST1 (IST1 factor associated with ESCRT-III).
Genome Resources: Alliance (1),  Gene:321460 (1),  Ensembl(GRCz11):ENSDARG00000051888 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7136831]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa21096 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34202 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ist1 N/A 1
    DISEASE ASSOCIATED WITH ist1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ist1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process axon extension (more)
    Cellular Component cellular_component (more)
    Molecular Function molecular_function (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ist1-201 (1)    Ensembl 2296
    ist1-202 (1)    Ensembl 2267
    ncRNA ist1-003 (1)    Ensembl 705
    ist1-004 (1)    Ensembl 1154
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-ist1 polyclonal IgG Rabbit Proteintech
    1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ist1 No data available
    MARKER RELATIONSHIPS
    ist1 Contained in: [BAC] DKEY-84O12 (1) (order this), DKEY-90B24 (1) (order this)
    ist1 Encodes: [EST] fb16b04, fi89e07 (1), IMAGE:7136831 (1)
    [cDNA] MGC:55671 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_212585 (1) 2311 nt
    Genomic GenBank:CR382281 (1) 143523 nt
    Select Tool
    Polypeptide UniProtKB:Q7ZVT1 (1) 354 aa
    Sequence Information (all 24)
    ORTHOLOGY for ist1 ( Chr: 7 )
    CITATIONS (22)