ZFIN ID: ZDB-GENE-030131-1229
Gene Name: actin alpha 2, smooth muscle
Gene Symbol: acta2
Sequence Ontology ID : SO:0000704

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Previous Names: sma (1), wu:fb63d03

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(Including Attributions)
Location: Ambiguous Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
GENE EXPRESSION
All Expression Data: 35 figures from 16 publications
Directly Submitted Expression Data: 7 figures (15 images) from Thisse et al., 2004 [MGC:92120]
  6 figures (6 images) from Rauch et al., 2003 [fb64d03]
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Larval:Day 6 (144.0h-168.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16546 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35248 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 3 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH acta2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Moyamoya disease Moyamoya disease 5 614042
    thoracic aortic aneurysm Aortic aneurysm, familial thoracic 6 611788
    Multisystemic smooth muscle dysfunction syndrome 613834
    DISEASE ASSOCIATED WITH acta2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process blood circulation (more)
    Cellular Component cell body (more)
    Molecular Function ATP binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR004000 (1)
  • InterPro:IPR004001 (1)
  • InterPro:IPR020902 (1)
  • PROSITE:PS00406 (1)
  • PROSITE:PS00432 (1)
  • PROSITE:PS01132 (1)
  • Pfam:PF00022 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA acta2-001 (1) 1369
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM acta2
    MARKER RELATIONSHIPS
    acta2Contained in: [BAC] CH73-369N22 (1) (order this)
    acta2Encodes: [EST] fb63d03, fb64d03 (1) (order this)
    [cDNA] MGC:92120 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212620 (1) 1600bp
    Genomic GenBank:FO704908 (1) 108766bp
    Select Tool
    Polypeptide UniProtKB:Q6DHS1 (1) 377aa
    Sequence Clusters UniGene:20277 (1)
    Sequence Information (all 19)
    OTHER acta2 GENE PAGES
  • Alliance (1)
  • Gene:322509 (1)
  • VEGA:OTTDARG00000035667 (1)
  • Ensembl(GRCz11):ENSDARG00000045180 (2)
  • ORTHOLOGY for acta2 (Ambiguous)
    CITATIONS (70)