ZFIN ID: ZDB-GENE-030128-4
Gene Name: SMAD family member 3b
Gene Symbol: smad3b
Sequence Ontology ID : SO:0000704

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Previous Names: madh3b, Smad3b (1), zgc:92234

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(Including Attributions)
Location: Chr: 18 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA binding activity and DNA-binding activity transcription factor activity; predicted to be involved in regulation of transcription, DNA-templated and transforming growth factor  ...
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Pharyngula:Prim-25 (36.0h-42.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa11128 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36632 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 3 figures from 3 publications
    Observed in:
    DISEASE ASSOCIATED WITH smad3b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Loeys-Dietz syndrome 3 Loeys-Dietz syndrome 3 613795
    DISEASE ASSOCIATED WITH smad3b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription, DNA-templated (more)
    Cellular Component cytoplasm (more)
    Molecular Function protein binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001132 (1)
  • InterPro:IPR003619 (1)
  • InterPro:IPR008984 (1)
  • InterPro:IPR013019 (1)
  • InterPro:IPR013790 (1)
  • InterPro:IPR017855 (1)
  • InterPro:IPR036578 (1)
  • PROSITE:PS51075 (1)
  • PROSITE:PS51076 (1)
  • Pfam:PF03165 (1)
  • Pfam:PF03166 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA smad3b-201 (1) 2167
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM smad3b No data available
    MARKER RELATIONSHIPS
    smad3bContained in: [BAC] DKEY-85G12 (1) (order this), DKEY-288J18 (1) (order this)
    smad3bEncodes: [cDNA] MGC:92234 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_175083 (1) 2030bp
    Genomic GenBank:CR533570 (1) 167352bp
    Select Tool
    Polypeptide UniProtKB:Q66HX9 (1) 423aa
    Sequence Clusters UniGene:85359 (1)
    Sequence Information (all 14)
    OTHER smad3b GENE PAGES
  • Alliance (1)
  • Gene:326283 (1)
  • VEGA:OTTDARG00000034658 (1)
  • Ensembl(GRCz11):ENSDARG00000010207 (2)
  • ORTHOLOGY for smad3b (Chr: 18)
    CITATIONS (38)