ZFIN ID: ZDB-GENE-030114-2
Gene Name: glutamate dehydrogenase 1a
Gene Symbol: glud1a    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: glud1, cb622 (1), wu:fc33g09, wu:fc66a10

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have glutamate dehydrogenase (NAD+) activity. Predicted to be involved in glutamate catabolic process. Predicted to localize to mitochondrion. Is expressed in several structures, including cardiovascular system; digestive system; nervous system; periderm; and pronephros. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 6; hyperinsulinism; and hypoglycemia. Orthologous to human GLUD1 (glutamate dehydrogenase 1).
Genome Resources: Alliance (1),  Gene:317737 (1),  Ensembl(GRCz11):ENSDARG00000008816 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa31925 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35471 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH glud1a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    familial hyperinsulinemic hypoglycemia 6 Alliance Hyperinsulinism-hyperammonemia syndrome 606762
    DISEASE ASSOCIATED WITH glud1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular amino acid metabolic process (more)
    Cellular Component mitochondrion (more)
    Molecular Function oxidoreductase activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA glud1a-201 (1)    Ensembl 2482
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM glud1a No data available
    MARKER RELATIONSHIPS
    glud1a Contained in: [BAC] CH211-134M17 (1)
    glud1a Encodes: [EST] cb622 (1) (order this), fc33g09 (1), fc66a10 (1) (order this)
    [cDNA] MGC:77186 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_212576 (1) 2520 nt
    Genomic GenBank:BX005174 (1) 178371 nt
    Select Tool
    Polypeptide UniProtKB:B8A4B0 (1) 544 aa
    Sequence Information (all 13)
    ORTHOLOGY for glud1a ( Chr: 13 )
    CITATIONS (33)