ZFIN ID: ZDB-GENE-021226-3
Gene Name: laminin, gamma 1
Gene Symbol: lamc1
Previous Names: shortstop, shp, sleepy, sly
Location: Chr: 2 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 13 figures from 7 publications
Directly Submitted Expression Data: 6 figures (20 images) from Thisse et al., 2004 [MGC:85930]
Wild-type Stages, Structures: Blastula:1k-cell (3.0h-3.33h) to Juvenile:Days 45-89 (45d-90d, 14 mm, 12 teeth)
  adaxial cell, brain, epidermis, eye (all 34) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
cz61 Point Mutation ENU
hi1193Tg Transgenic Insertion DNA
hi2557Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • hi3890Tg Transgenic Insertion DNA
    hi4131Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la023638Tg Transgenic Insertion DNA
    la023639Tg Transgenic Insertion DNA
    la028800Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la028801Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • lamc1_unspecified Unspecified
    m86 Point Mutation ENU
    m91 Unknown ENU
    m99 Unknown ENU
    m152 Unknown ENU
    m253 Unknown ENU
    m388 Unknown ENU
    m466 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m515 Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m516 Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m707 Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa379 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa9866 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • te223 Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • te333 Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tf215b Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • ti263a Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • ti272a Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tm89 Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • to216a Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tp16 Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • ts33a Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • wi390Tg Transgenic Insertion DNA
    Targeting reagents: MO1-lamc1 (1), MO2-lamc1 (1), MO3-lamc1 (1)
    PHENOTYPE
    Data: 62 figures from 23 publications
    Observed in: actin filament organization, anterior/posterior axon guidance, axon extension, axon guidance (all 59) expand
    DISEASE ASSOCIATED WITH lamc1 HUMAN ORTHOLOG No data available
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process axon guidance (more)
    Cellular Component basement membrane (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000034 (1)
  • InterPro:IPR002049 (1)
  • InterPro:IPR008211 (1)
  • PROSITE:PS00022 (1)
  • PROSITE:PS01186 (1)
  • PROSITE:PS01248 (1)
  • PROSITE:PS50027 (1)
  • PROSITE:PS51115 (1)
  • PROSITE:PS51117 (1)
  • Pfam:PF00052 (1)
  • Pfam:PF00053 (1)
  • Pfam:PF00055 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA lamc1-001 (1) 6133
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lamc1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    lamc1Contained in: [BAC] CH211-194I4 (1) (order this), DKEY-161L11 (1) (order this)
    lamc1Encodes: [cDNA] MGC:85930 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_173277 (1) 6055bp
    Genomic GenBank:BX681417 (1) 233760bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q1LVF0 (1) 1593aa
    Sequence Clusters UniGene:132970 (1)
    Sequence Information (all 14)
    OTHER lamc1 GENE PAGES 
  • Gene:286832 (1)
  • VEGA:OTTDARG00000017017 (1)
  • Ensembl(GRCz10):ENSDARG00000036279 (1)
  • ORTHOLOGY for lamc1 (Chr: 2) 
    Species Symbol Chromosome Accession # Evidence
    Human LAMC1 1
  • Gene:3915
  • OMIM:150290
  • HGNC:6492
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (1)
    Mouse Lamc1 1
  • MGI:99914
  • Gene:226519
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Other (1)
    Download Curated Orthology
    CITATIONS (70)