ZFIN ID: ZDB-GENE-021226-3
Gene Name: laminin, gamma 1
Gene Symbol: lamc1
Previous Names: shortstop, shp, sleepy, sly
Location: Chr: 2 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 13 figures from 7 publications
Directly Submitted Expression Data: 6 figures (20 images) from Thisse et al., 2004 [MGC:85930]
Wild-type Stages, Structures: Blastula:1k-cell (3.0h-3.33h) to Juvenile:Days 45-89 (45d-90d, 14 mm, 12 teeth)
  adaxial cell, brain, epidermis, eye (all 34) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
cz61 Point Mutation Unknown Unknown ENU
hi1193Tg Transgenic Insertion Unknown Unknown DNA
hi2557Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • hi3890Tg Transgenic Insertion Unknown Unknown DNA
    hi4131Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la023638Tg Transgenic Insertion Unknown Unknown DNA
    la023639Tg Transgenic Insertion Unknown Unknown DNA
    la028800Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la028801Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • lamc1_unspecified Unspecified Unknown Unknown
    m86 Point Mutation Unknown Premature Stop ENU
    m91 Unknown Unknown Unknown ENU
    m99 Unknown Unknown Unknown ENU
    m152 Unknown Unknown Unknown ENU
    m253 Unknown Unknown Unknown ENU
    m388 Unknown Unknown Unknown ENU
    m466 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m515 Unknown Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m516 Unknown Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m707 Unknown Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa379 Point Mutation Acceptor Splice Site Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa9866 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa30600 Point Mutation Unknown Unknown ENU
    sa39876 Point Mutation Unknown Unknown ENU
    te223 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • te333 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tf215b Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • ti263a Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • ti272a Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tm89 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • to216a Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tp16 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • ts33a Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • wi390Tg Transgenic Insertion Unknown Unknown DNA
    Targeting reagents: MO1-lamc1 (1), MO2-lamc1 (1), MO3-lamc1 (1)
    PHENOTYPE
    Data: 63 figures from 23 publications
    Observed in: actin filament organization, anterior/posterior axon guidance, axon extension, axon guidance (all 60) expand
    DISEASE ASSOCIATED WITH lamc1 HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process axon guidance (more)
    Cellular Component basement membrane (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000034 (1)
  • InterPro:IPR000742 (1)
  • InterPro:IPR002049 (1)
  • InterPro:IPR008211 (1)
  • InterPro:IPR011641 (1)
  • PROSITE:PS00022 (1)
  • PROSITE:PS01186 (1)
  • PROSITE:PS01248 (1)
  • PROSITE:PS50027 (1)
  • PROSITE:PS51115 (1)
  • PROSITE:PS51117 (1)
  • Pfam:PF00052 (1)
  • Pfam:PF00053 (1)
  • Pfam:PF00055 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA lamc1-001 (1) 6133
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM lamc1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    lamc1Contained in: [BAC] CH211-194I4 (1) (order this), DKEY-161L11 (1) (order this)
    lamc1Encodes: [cDNA] MGC:85930 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_173277 (1) 6055bp
    Genomic GenBank:BX681417 (1) 233760bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q1LVF0 (1) 1593aa
    Sequence Clusters UniGene:132970 (1)
    Sequence Information (all 14)
    OTHER lamc1 GENE PAGES
  • Gene:286832 (1)
  • VEGA:OTTDARG00000017017 (1)
  • Ensembl(GRCz10):ENSDARG00000036279 (1)
  • ORTHOLOGY for lamc1 (Chr: 2)
    Species Symbol Chromosome Accession # Evidence
    Human LAMC1 1
  • Gene:3915
  • OMIM:150290
  • HGNC:6492
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (1)
    Mouse Lamc1 1
  • MGI:99914
  • Gene:226519
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Other (1)
    Download Curated Orthology
    CITATIONS (71)