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ZIRC
ZFIN ID: ZDB-GENE-021226-3
Gene Name: laminin, gamma 1
Gene Symbol: lamc1    Nomenclature History

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Previous Names: shortstop, shp, sleepy, sly

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have extracellular matrix structural constituent. Involved in several processes, including animal organ development; detection of light stimulus involved in visual perception; and retinal ganglion cell axon guidance. Predicted to localize to the basement membrane. Is expressed in several structures, including central nervous system; eye; median fin fold; musculature system; and optic cup. Orthologous to human LAMC1 (laminin subunit gamma 1).
Genome Resources: Alliance (1),  Gene:286832 (1),  Ensembl(GRCz11):ENSDARG00000036279 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
cz61 Point Mutation Intron 26 Unknown ENU
hi1193Tg Transgenic Insertion Intron 1 Unknown DNA
hi2557Tg Transgenic Insertion Exon 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • hi3890Tg Transgenic Insertion Intron 1 Unknown DNA
    hi4131Tg Transgenic Insertion Intron 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la023638Tg Transgenic Insertion Unknown Unknown DNA
    la023639Tg Transgenic Insertion Unknown Unknown DNA
    la028800Tg Transgenic Insertion Unknown Unknown DNA
    la028801Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • lamc1_unspecified Unspecified Unknown Unknown
    m86 Point Mutation Unknown Premature Stop ENU
    m91 Unknown Unknown Unknown ENU
    m99 Unknown Unknown Unknown ENU
    m152 Unknown Unknown Unknown ENU
    m253 Unknown Unknown Unknown ENU
    m388 Unknown Unknown Unknown ENU
    m466 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m515 Unknown Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m516 Unknown Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m707 Unknown Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa379 Point Mutation Acceptor Splice Site Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa9866 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19814 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa30600 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39876 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • te223 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • te333 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tf215b Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • ti263a Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • ti272a Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tm89 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • to216a Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tp16 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • ts33a Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • wi390Tg Transgenic Insertion Unknown Unknown DNA
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-lamc1 N/A 1
    MO2-lamc1 N/A 2
    MO3-lamc1 N/A 12
    DISEASE ASSOCIATED WITH lamc1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH lamc1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process axon guidance (more)
    Cellular Component basement membrane (more)
    Molecular Function extracellular matrix structural constituent (more)
    GO Terms (all 20)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA lamc1-201 (1)    Ensembl 6133
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lamc1 No data available
    MARKER RELATIONSHIPS
    lamc1 Contained in: [BAC] CH211-194I4 (1) (order this), DKEY-161L11 (1) (order this)
    lamc1 Encodes: [cDNA] MGC:85930 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_173277 (1) 6055 bp
    Genomic GenBank:BX681417 (1) 233760 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q1LVF0 (1) 1593 aa
    Sequence Clusters UniGene:132970 (1)
    Sequence Information (all 15)
    ORTHOLOGY for lamc1 ( Chr: 2 )
    CITATIONS (88)