ZFIN ID: ZDB-GENE-021226-3
Gene Name: laminin, gamma 1
Gene Symbol: lamc1
Previous Names: shortstop, shp, sleepy, sly
Location: Chr: 2   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 12 figures from 6 publications
Directly Submitted Expression Data: 6 figures (20 images) from Thisse et al., 2004 [MGC:85930]
Wild-type Stages, Structures: Blastula:1k-cell (3.0h-3.33h) to Juvenile:Days 45-89 (45d-90d, 14 mm, 12 teeth)
  adaxial cell, brain, epidermis, eye (all 34) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 48 Genotypes
Knockdown reagents: MO1-lamc1 (1), MO2-lamc1 (1), MO3-lamc1 (1)

Allele Type Mutagen Suppliers
cz61 Point Mutation ENU
hi1193Tg Transgenic Insertion DNA
hi2557Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • hi3890Tg Transgenic Insertion DNA
    hi4131Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  •    expand Show all 32 alleles
    PHENOTYPE
    Data: 62 figures from 23 publications
    Observed in: actin filament organization, anterior/posterior axon guidance, axon extension, axon guidance (all 59) expand
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process brain development (more)
    Cellular Component basement membrane (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000034 (1)
  • InterPro:IPR002049 (1)
  • InterPro:IPR008211 (1)
  • InterPro:IPR018031 (1)
  • PROSITE:PS00022 (1)
  • PROSITE:PS01186 (1)
  • PROSITE:PS01248 (1)
  • PROSITE:PS50027 (1)
  • PROSITE:PS51115 (1)
  • PROSITE:PS51117 (1)
  • Pfam:PF00052 (1)
  • Pfam:PF00053 (1)
  • Pfam:PF00055 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA lamc1-001 (1) 6133
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lamc1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    lamc1 Contained in: [BAC] CH211-194I4 (1) (order this), DKEY-161L11 (1) (order this)
    lamc1 Encodes: [cDNA] MGC:85930 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_173277 (1) 6055 bp
    Genomic GenBank:BX681417 (1) 233760 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q1LVF0 (1) 1593 aa
    Sequence Clusters UniGene:132970 (1)
    Sequence Information (all 14)
    OTHER lamc1 GENE PAGES
  • Gene:286832 (1)
  • VEGA:OTTDARG00000017017 (1)
  • Ensembl(Zv9):ENSDARG00000036279 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL IX
    Zebrafish lamc1 2  
    Human LAMC1 1 (1q31)
  • OMIM:150290
  • Gene:3915
  • Mouse Lamc1 1 ( 65.30 cM)
  • MGI:99914
  • Gene:226519
  • Orthology Details
    CITATIONS (68)