Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-021226-3
Gene Name: laminin, gamma 1
Gene Symbol: lamc1
Previous Names: shortstop, shp, sleepy, sly
Location: Chr: 2   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 12 figures from 6 publications
Directly Submitted Expression Data: 6 figures (20 images) from Thisse et al., 2004 [MGC:85930]
Wild-type Stages, Structures: Blastula:1k-cell (3.0h-3.33h) to Juvenile:Days 45-89 (45d-90d, 14 mm, 12 teeth)
  adaxial cell, brain, epidermis, eye (all 33) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 48 genotypes
Alleles: cz61, hi1193Tg, hi2557Tg, hi3890Tg, hi4131Tg (all 32) expand
Knockdown reagents: MO1-lamc1 (1), MO2-lamc1 (1), MO3-lamc1 (1)
PHENOTYPE
Data: 62 figures from 23 publications
Observed in: actin filament organization, anterior/posterior axon guidance, axon extension, axon guidance (all 59) expand
GENE ONTOLOGY
Ontology GO Term
Biological Process detection of light stimulus involved in visual perception (more)
Cellular Component basement membrane (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000034 (1)
  • InterPro:IPR002049 (1)
  • InterPro:IPR008211 (1)
  • InterPro:IPR018031 (1)
  • PROSITE:PS00022 (1)
  • PROSITE:PS01186 (1)
  • PROSITE:PS01248 (1)
  • PROSITE:PS50027 (1)
  • PROSITE:PS51115 (1)
  • PROSITE:PS51117 (1)
  • Pfam:PF00052 (1)
  • Pfam:PF00053 (1)
  • Pfam:PF00055 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA lamc1-001 (1) 6133
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lamc1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    lamc1 Contained in: [BAC] CH211-194I4 (1) (order this), DKEY-161L11 (1)
    lamc1 Encodes: [cDNA] MGC:85930 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_173277 (1) 6055 bp
    Genomic GenBank:BX681417 (1) 233760 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q1LVF0 (1) 1593 aa
    Sequence Clusters UniGene:132970 (1)
    Sequence Information (all 14)
    OTHER lamc1 GENE PAGES
  • Gene:286832 (1)
  • VEGA:OTTDARG00000017017 (1)
  • Ensembl(Zv9):ENSDARG00000036279 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL IX
    Zebrafish lamc1 2  
    Human LAMC1 1 (1q31)
  • OMIM:150290
  • Gene:3915
  • Mouse Lamc1 1 ( 65.30 cM)
  • MGI:99914
  • Gene:226519
  • Orthology Details
    CITATIONS (65)