ZFIN ID: ZDB-GENE-021220-3
Gene Name: doublesex and mab-3 related transcription factor 3a
Gene Symbol: dmrt3a    Nomenclature History

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Previous Names: Dmrt3 (1), zDmart3a (1), zDmrt3a-1, zgc:101766

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Exhibits sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to localize to the nucleus. Is expressed in nervous system; neural tube; and reproductive system. Orthologous to human DMRT3 (doublesex and mab-3 related transcription factor 3).
Genome Resources: Alliance (1),  Gene:450035 (1),  Ensembl(GRCz11):ENSDARG00000035290 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa15557 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40540 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dmrt3a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dmrt3a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription, DNA-templated (more)
    Cellular Component nucleus (more)
    Molecular Function sequence-specific DNA binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001275 DM DNA-binding domain
    Domain IPR005173 DMRTA motif
    Homologous_superfamily IPR009060 UBA-like superfamily
    Family IPR026607 DMRT/protein doublesex/protein male abnormal 3
    Homologous_superfamily IPR036407 DM DNA-binding domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dmrt3a-201 (1)    Ensembl 1920
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dmrt3a
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    TgBAC(dmrt3a:GAL4FF) dmrt3a GAL4FF Danio rerio 1 2
    TgBAC(dmrt3a:LOXP-RFP-LOXP-GFP) dmrt3a GFPRFP Danio rerio 1 2
    MARKER RELATIONSHIPS
    dmrt3a Contained in: [BAC] DKEYP-31E5 (1)
    dmrt3a Encodes: [EST] eu876 (1)
    [cDNA] MGC:101766 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001005779 (1)
    Genomic RefSeq:NW_018394607 (1) Blast at MegaBLAST
    Polypeptide UniProtKB:P83758 (1) 448 aa
    Sequence Information (all 19)
    ORTHOLOGY for dmrt3a ( Chr: 5 )
    CITATIONS (32)