ZFIN ID: ZDB-GENE-021211-3
Gene Name: hatching enzyme 1, tandem duplicate 1
Gene Symbol: he1.1    Nomenclature History

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Previous Names: he1, he1a (1), cb284 (1), wu:cegs2099, zgc:111847

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have metalloendopeptidase activity. Predicted to be involved in proteolysis. Is expressed in hatching gland and polster. Orthologous to human ASTL (astacin like metalloendopeptidase).
Genome Resources: Alliance (1),  Gene:569018 (1),  Ensembl(GRCz11):ENSDARG00000023656 (1)
GENE EXPRESSION
All Expression Data: 21 figures from 5 publications
Directly Submitted Expression Data: 6 figures (9 images) from Thisse et al., 2001 [cb284]
  12 figures (29 images) from Rauch et al., 2003 [cegs2099]
Wild-type Stages, Structures: Gastrula:Bud (10.0h-10.33h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH he1.1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH he1.1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process proteolysis (more)
Molecular Function hydrolase activity (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA he1.1-202 (1)    Ensembl 1057
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
CONSTRUCTS WITH SEQUENCES FROM he1.1
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(2xen.cpce-E1B:KALNFB,he1.1:mTagBFP2) E1Ben.cpcehe1.1 KALTagBFP Danio rerio 1 2
Tg(2xNRSE-LOXP-5xUAS-E1B:GAP-YFP-LOXP,he1.1:GAP-YFP) E1Bhe1.1LOXPNRSEUAS GAPLOXPYFP Danio rerio 1 2
Tg(LOXP-5xUAS-E1B:GAP-YFP-LOXP,he1.1:GAP-YFP) E1Bhe1.1UAS YFP Danio rerio 3 3
tg(lyz:kalta4,he1.1:bfp2) he1.1lyz BFPKALTA4 Danio rerio 1 1
tg(mpeg1.1:kalta4,he1.1:bfp2) he1.1mpeg1.1 BFPKALTA4 Danio rerio 1 1
MARKER RELATIONSHIPS
he1.1 Contained in: [BAC] CH211-246M6 (1)
he1.1 Encodes: [EST] cb284 (1) (order this), cegs2099 (1) (order this)
[cDNA] MGC:111847 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001045174 (1)
Genomic GenBank:BX649296 (1) 175492 nt
Select Tool
Polypeptide UniProtKB:Q1LW00 (1) 263 aa
Sequence Information (all 16)
ORTHOLOGY for he1.1 ( Chr: 22 )
CITATIONS (43)