Gene

slc11a2

ID
ZDB-GENE-021115-1
Name
solute carrier family 11 member 2
Symbol
slc11a2 Nomenclature History
Previous Names
  • cdy
  • DMT1 (1)
  • cb426 (1)
  • chardonnay
  • fa07b10
  • nramp (1)
  • wu:fa07b10
  • zgc:136699 (1)
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Exhibits iron ion transmembrane transporter activity. Involved in several processes, including embryonic hemopoiesis; hemoglobin biosynthetic process; and response to copper ion. Predicted to localize to plasma membrane. Is expressed in several structures, including alar plate midbrain region; digestive system; lens; solid lens vesicle; and ventral mesoderm. Human ortholog(s) of this gene implicated in Parkinson's disease; amyotrophic lateral sclerosis; anemia; and hypochromic anemia. Orthologous to human SLC11A2 (solute carrier family 11 member 2).
Genome Resources
Note
None
Expression
All Expression Data
9 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slc11a2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hypochromic microcytic anemia Alliance Anemia, hypochromic microcytic, with iron overload 1 206100
Associated With slc11a2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR001046 NRAMP family
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations