ZFIN ID: ZDB-GENE-021030-3
Gene Name: cystathionine-beta-synthase b
Gene Symbol: cbsb
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: cbs, cb442 (1), wu:fb37g05, wu:fm61c07, wu:fq06c06, zgc:113704

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 19 figures from 4 publications
Directly Submitted Expression Data: 6 figures (16 images) from Rauch et al., 2003 [fb83h03]
  6 figures (20 images) from Thisse et al., 2001 [cb442]
  6 figures (15 images) from Thisse et al., 2004 [IMAGE:7147404]
Wild-type Stages, Structures: Blastula:30%-epiboly (4.66h-5.25h) to Hatching:Long-pec (48.0h-60.0h)
  anterior axial hypoblast, immature eye, lens, mesoderm (all 20) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa27348 Point Mutation Unknown Premature Stop ENU
sa38725 Point Mutation Unknown Splice Site ENU
Targeting reagents: MO1-cbsb (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH cbsb HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
homocystinuria Homocystinuria, B6-responsive and nonresponsive types 236200
Thrombosis, hyperhomocysteinemic 236200
GENE ONTOLOGY
Ontology GO Term
Biological Process cellular amino acid biosynthetic process (more)
Cellular Component cytoplasm (more)
Molecular Function cystathionine beta-synthase activity (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000644 (1)
  • InterPro:IPR001216 (1)
  • InterPro:IPR001926 (1)
  • InterPro:IPR005857 (1)
  • InterPro:IPR036052 (1)
  • PROSITE:PS00901 (1)
  • PROSITE:PS51371 (1)
  • Pfam:PF00291 (1)
  • Pfam:PF00571 (1)
  • EC:4.2.1.22 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cbsb-001 (1) 2561
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM cbsb No data available
    MARKER RELATIONSHIPS
    cbsbContained in: [BAC] CH211-214P13 (1) (order this)
    [Fosmid] CH1073-392N17 (1) (order this)
    cbsbEncodes: [EST] cb442 (1) (order this), fb37g05, fb83h03 (1) (order this), fm61c07 (1), fq06c06 (1), IMAGE:7147404 (1) (order this)
    [cDNA] MGC:113704 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001014345 (1) 2868bp
    Genomic GenBank:AL954142 (1) 238837bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1QIC0 (1) 597aa
    Sequence Clusters UniGene:76887 (1)
    Sequence Information (all 26)
    OTHER cbsb GENE PAGES
  • Alliance (1)
  • Gene:266987 (1)
  • VEGA:OTTDARG00000032777 (1)
  • Ensembl(GRCz10):ENSDARG00000010946 (1)
  • ORTHOLOGY for cbsb (Chr: 9)
    CITATIONS (28)