ZFIN ID: ZDB-GENE-020925-1
Gene Name: dynein, axonemal, heavy chain 9
Gene Symbol: dnah9    Nomenclature History

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Previous Names: dnahc11, fj30b09, lrdr1 (1), Lrdr (1), wu:fj30b09, zgc:63607

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have ATP-dependent microtubule motor activity, minus-end-directed; dynein intermediate chain binding activity; and dynein light intermediate chain binding activity. Involved in epithelial cilium movement involved in determination of left/right asymmetry. Predicted to localize to axoneme; dynein complex; and motile cilium. Is expressed in several structures, including mesoderm; nervous system; neural tube; pleuroperitoneal region; and tail bud. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 40. Orthologous to human DNAH9 (dynein axonemal heavy chain 9).
Genome Resources: Alliance (1),  Gene:266676 (1),  Ensembl(GRCz11):ENSDARG00000103383 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1198 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21988 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-dnah9 N/A 3
    MO2-dnah9 N/A 1
    MO3-dnah9 N/A 2
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dnah9 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    primary ciliary dyskinesia 40 Alliance Ciliary dyskinesia, primary, 40 618300
    DISEASE ASSOCIATED WITH dnah9 VIA EXPERIMENTAL MODELS No data available
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dnah9-001 (1) 5140
    dnah9-201 (1)    Ensembl 1964
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dnah9 No data available
    MARKER RELATIONSHIPS
    dnah9 Contained in: [Fosmid] CH1073-80J9 (1)
    dnah9 Encodes: [cDNA] MGC:63607
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001366550 (1)
    Genomic GenBank:CU607078 (1) 35630 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4IUQ6 (1) 614 aa
    Sequence Information (all 17)
    ORTHOLOGY for dnah9 ( Chr: 12 )
    CITATIONS (50)