ZFIN ID: ZDB-GENE-020916-2
Gene Name: eukaryotic elongation factor 2 kinase
Gene Symbol: eef2k    Nomenclature History

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Previous Names: cb365 (1), fa04b08, wu:fa04b08, zgc:100973

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have several functions, including ATP binding activity; calmodulin binding activity; and elongation factor-2 kinase activity. Involved in cerebellum vasculature development. Is expressed in epidermis; hatching gland; musculature system; and myotome. Orthologous to human EEF2K (eukaryotic elongation factor 2 kinase).
Genome Resources: Alliance (1),  Gene:437013 (1),  Ensembl(GRCz11):ENSDARG00000035835 (2)
GENE EXPRESSION
All Expression Data: 11 figures from 3 publications
Directly Submitted Expression Data: 3 figures (4 images) from Thisse et al., 2001 [cb365]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7137793]
  6 figures (3 images) from Thisse et al., 2004 [IMAGE:7147999]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la018018Tg Transgenic Insertion Unknown Unknown DNA
sa35222 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41972 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-eef2k N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH eef2k HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH eef2k VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cerebellum vasculature development (more)
    Molecular Function ATP binding (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA eef2k-201 (1)    Ensembl 2970
    eef2k-202 (1)    Ensembl 2501
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM eef2k No data available
    MARKER RELATIONSHIPS
    eef2k Contained in: [BAC] CH73-389D14 (1)
    eef2k Encodes: [EST] cb365 (1) (order this), fa04b08 (1), IMAGE:7137793 (1), IMAGE:7147999 (1)
    [cDNA] MGC:100973 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001002740 (1) 2995 nt
    Genomic GenBank:CU104767 (1) 82367 nt
    Select Tool
    Polypeptide UniProtKB:E7F318 (1) 744 aa
    Sequence Information (all 23)
    ORTHOLOGY for eef2k ( Chr: 12 )
    CITATIONS (29)