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General Information
ZIRC
ZFIN ID: ZDB-GENE-020905-4
Gene Name: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b
Gene Symbol: mthfd1b
Sequence Ontology ID : SO:0000704

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Previous Names: mthfd1 (1), cb325 (1), fc29f07, formyltetrahydrofolate synthetase, methenyltetrahydrofolate cyclohydrolase, wu:fc29f07

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(Including Attributions)
Location: Chr: 17 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have formate-tetrahydrofolate ligase activity; methenyltetrahydrofolate cyclohydrolase activity; and methylenetetrahydrofolate dehydrogenase (NADP+) activity. Predicted to be involved in  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la027878Tg Transgenic Insertion Unknown Unknown DNA
sa473 Point Mutation Unknown Premature Stop ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH mthfd1b HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
neural tube defect {Neural tube defects, folate-sensitive, susceptibility to} 601634
Combined immunodeficiency and megaloblastic anemia with or without hyperhomocysteinemia 617780
Combined immunodeficiency and megaloblastic anemia with or without hyperhomocysteinemia 617780
DISEASE ASSOCIATED WITH mthfd1b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process oxidation-reduction process (more)
Cellular Component cytoplasm (more)
Molecular Function ATP binding (more)
GO Terms (all 9)
TRANSCRIPTS
Type Name Length (bp) Analysis
ncRNA mthfd1b-003 (1) 487
mRNA mthfd1b-201 (1) 3134
aberrant processed transcript mthfd1b-203 (1) 332
mRNA mthfd1b-204 (1) 349
GENE PRODUCT DESCRIPTION No description available
INTERACTIONS AND PATHWAYS
ANTIBODIESNo data available
PLASMIDSNo data available
CONSTRUCTS WITH SEQUENCES FROM mthfd1b No data available
MARKER RELATIONSHIPS
mthfd1bContained in: [BAC] CH73-73N15 (1) (order this), CH73-199K24 (1) (order this)
mthfd1bContains: [SNP] rs3728884 (1)
mthfd1bEncodes: [EST] cb325 (1) (order this), fc29f07, IMAGE:6912136 (1) (order this)
[cDNA] MGC:55597 (1) (order this), MGC:86856 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_199529 (1) 3097bp
Genomic GenBank:AL954689 (1) 157208bp
Select Tool
Polypeptide UniProtKB:F1QXP5 (1) 934aa
Sequence Clusters UniGene:7124 (1)
Sequence Information (all 25)
ORTHOLOGY for mthfd1b (Chr: 17)
CITATIONS (27)