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General Information
ZIRC
ZFIN ID: ZDB-GENE-020905-3
Gene Name: mutS homolog 6 (E. coli)
Gene Symbol: msh6
Sequence Ontology ID : SO:0001217

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Previous Names: cb326 (1), wu:fb36c12

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(Including Attributions)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits guanine/thymine mispair binding activity. Predicted to contribute to MutLalpha complex binding activity; oxidized purine DNA binding activity; and single thymine insertion binding activity.  ...
DISEASE ASSOCIATED WITH msh6 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
endometrial cancer {Endometrial cancer, familial} 608089
hereditary nonpolyposis colorectal cancer type 5 Colorectal cancer, hereditary nonpolyposis, type 5 614350
Mismatch repair cancer syndrome 276300
DISEASE ASSOCIATED WITH msh6 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process maintenance of DNA repeat elements (more)
Cellular Component mismatch repair complex (more)
Molecular Function double-stranded DNA binding (more)
GO Terms (all 24)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA msh6-201 (1) 444
msh6-202 (1) 801
msh6-203 (1) 426
msh6-204 (1) 4396
GENE PRODUCT DESCRIPTION
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM msh6 No data available
MARKER RELATIONSHIPS
msh6 Contained in: [Fosmid] CH1073-436F10 (1) (order this)
msh6 Contains: [SNP] rs3728599 (1)
msh6 Encodes: [EST] cb326 (1) (order this), fb36c12
[cDNA] MGC:55252 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_182860 (1) 4385 bp
Genomic GenBank:CU468002 (1) 32834 bp
Select Tool
Polypeptide UniProtKB:A0A0R4IAE0 (1) 1369 aa
Sequence Clusters UniGene:4108 (1)
Sequence Information (all 21)
ORTHOLOGY for msh6 ( Chr: 13 )
CITATIONS (38)