Gene
copa
- ID
- ZDB-GENE-020905-2
- Name
- COPI coat complex subunit alpha
- Symbol
- copa Nomenclature History
- Previous Names
-
- cb281 (1)
- fb13c12
- sneezy
- wu:fb13c12
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Is predicted to enable structural molecule activity. Involved in Golgi vesicle transport and intracellular protein transport. Acts upstream of or within notochord development and somite development. Predicted to be located in Golgi membrane. Predicted to be part of COPI vesicle coat. Is expressed in several structures, including axis; hatching gland; mesoderm; notochord; and pectoral fin. Orthologous to human COPA (COPI coat complex subunit alpha).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb281 (6 images)
- IMAGE:7152734 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 22 figures from 7 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Autoimmune interstitial lung, joint, and kidney disease} | 616414 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Domain | IPR006692 | Coatomer, WD associated region |
| Domain | IPR010714 | Coatomer, alpha subunit, C-terminal |
| Family | IPR016391 | Coatomer alpha subunit |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
| Repeat | IPR020472 | G-protein beta WD-40 repeat |
Domain Details Per Protein
| Protein | Length | Coatomer alpha subunit | Coatomer, alpha subunit, C-terminal | Coatomer, WD associated region | G-protein beta WD-40 repeat | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1QDQ1
|
1224 | ||||||||
|
UniProtKB:A0A286Y8Z3
|
538 | ||||||||
|
UniProtKB:Q6JWU9
|
1226 | ||||||||
|
UniProtKB:Q6DRK5
|
1224 | ||||||||
|
UniProtKB:A7E2H7
|
538 | ||||||||
|
UniProtKB:B3DGP8
|
1224 |
Interactions and Pathways
No data available
Plasmids
No data available