ZFIN ID: ZDB-GENE-020905-2
Gene Name: COPI coat complex subunit alpha
Gene Symbol: copa    Nomenclature History

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Previous Names: cb281 (1), fb13c12, sneezy, wu:fb13c12

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have structural molecule activity. Involved in notochord development and somite development. Predicted to localize to COPI vesicle coat. Is expressed in several structures, including axis; hatching gland; mesoderm; notochord; and pectoral fin. Orthologous to human COPA (COPI coat complex subunit alpha).
Genome Resources: Alliance (1),  Gene:260439 (1),  Ensembl(GRCz11):ENSDARG00000004173 (2)
GENE EXPRESSION
All Expression Data: 10 figures from 5 publications
Directly Submitted Expression Data: 6 figures (6 images) from Thisse et al., 2001 [cb281]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7152734]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi1872Tg Transgenic Insertion 5' UTR Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • hi2203Tg Transgenic Insertion Intron 1 Unknown DNA
    hi3669Tg Transgenic Insertion Intron 1 Unknown DNA
    la010427Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m456 Point Mutation Donor Splice Site Cryptic Acceptor Splice Site, Frameshift, Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • td204a Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tm11 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tm75 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tn211 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tq249b Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-copa N/A 1
    DISEASE ASSOCIATED WITH copa HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    {Autoimmune interstitial lung, joint, and kidney disease} 616414
    DISEASE ASSOCIATED WITH copa VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process notochord development (more)
    Cellular Component COPI vesicle coat (more)
    Molecular Function structural molecule activity (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA copa-201 (1)    Ensembl 4131
    ncRNA copa-002 (1)    Ensembl 717
    copa-003 (1)    Ensembl 791
    copa-004 (1)    Ensembl 784
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM copa No data available
    MARKER RELATIONSHIPS
    copa Contained in: [BAC] DKEY-52K20 (1) (order this)
    copa Encodes: [EST] cb281 (1) (order this), fb13c12, IMAGE:7152734 (1)
    [cDNA] MGC:171377 (1), MGC:193571 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001001941 (1) 4261 nt
    Genomic GenBank:BX649372 (1) 249584 nt Blast at MegaBLAST
    Polypeptide UniProtKB:Q6JWU9 (1) 1226 aa
    Sequence Information (all 26)
    ORTHOLOGY for copa ( Chr: 2 )
    CITATIONS (46)