Gene

copa

ID

ZDB-GENE-020905-2

Name

COPI coat complex subunit alpha

Symbol

copa Nomenclature History

Previous Names

cb281 (1)
fb13c12
sneezy
wu:fb13c12

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to have structural molecule activity. Involved in notochord development and somite development. Predicted to localize to COPI vesicle coat. Is expressed in several structures, including axis; hatching gland; mesoderm; notochord; and pectoral fin. Orthologous to human COPA (COPI coat complex subunit alpha).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

10 figures from 5 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

cb281 (6 images)
IMAGE:7152734 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 22 figures from 7 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With copa Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		{Autoimmune interstitial lung, joint, and kidney disease}	616414

Associated With copa Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019775	WD40 repeat, conserved site
Domain	IPR006692	Coatomer, WD associated region
Domain	IPR010714	Coatomer, alpha subunit, C-terminal
Family	IPR016391	Coatomer alpha subunit
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001680	WD40 repeat
Repeat	IPR020472	G-protein beta WD-40 repeat

Domain Details Per Protein

Protein	Length	Coatomer alpha subunit	Coatomer, alpha subunit, C-terminal	Coatomer, WD associated region	G-protein beta WD-40 repeat	WD40 repeat	WD40 repeat, conserved site	WD40-repeat-containing domain superfamily	WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:F1QDQ1 InterPro	1224
UniProtKB:A0A286Y8Z3 InterPro	538
UniProtKB:Q6JWU9 InterPro	1226
UniProtKB:Q6DRK5 InterPro	1224
UniProtKB:A7E2H7 InterPro	538
UniProtKB:B3DGP8 InterPro	1224

Transcripts

Genome Browsers

Type	Name	Length (nt)	Analysis
mRNA	copa-201 (1) Ensembl	4131 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	copa-002 (1) Ensembl	717 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	copa-003 (1) Ensembl	791 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	copa-004 (1) Ensembl	784 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations