Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-020905-1
Gene Name: ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
Gene Symbol: atp2a1
Previous Names: acc, cb279 (1), serca (1), serca1 (1), accordion, wu:cegs655, wu:fb17h11, wu:fb19b10, zgc:92110
Location: Chr: 3   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 37 figures from 9 publications
Directly Submitted Expression Data: 7 figures (15 images) from Rauch et al., 2003 [fb19b10]
  12 figures (21 images) from Rauch et al., 2003 [fb39d07]
  4 figures (7 images) from Thisse et al., 2001 [cb279]
  7 figures (22 images) from Rauch et al., 2003 [cegs655]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
  adaxial cell, eye, mesoderm, musculature system (all 11) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 13 genotypes
Alleles: dta5, mi25i, mi289a, sa10632, sa16659 (all 13) expand
PHENOTYPE
Data: 12 figures from 3 publications
Observed in: locomotion, musculoskeletal movement, neuromuscular process controlling balance, notochord (all 9) expand

Phenotype of Human Orthologue OMIM Phenotype ID
Brody myopathy 601003
GENE ONTOLOGY
Ontology GO Term
Biological Process cellular calcium ion homeostasis (more)
Cellular Component H zone (more)
Molecular Function ATP binding (more)
GO Terms (all 26)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001757 (1)
  • InterPro:IPR004014 (1)
  • InterPro:IPR005782 (1)
  • InterPro:IPR006068 (1)
  • InterPro:IPR008250 (1)
  • InterPro:IPR018303 (1)
  • InterPro:IPR023214 (1)
  • InterPro:IPR023298 (1)
  • InterPro:IPR023299 (1)
  • PROSITE:PS00154 (1)
  • Pfam:PF00122 (1)
  • Pfam:PF00689 (1)
  • Pfam:PF00690 (1)
  • Pfam:PF00702 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA atp2a1-001 (1) 3390
    atp2a1-002 (1) 3311
    ncRNA atp2a1-003 (1) 520
    atp2a1-004 (1) 348
    mRNA atp2a1-005 (1) 416
    atp2a1-006 (1) 1049
    atp2a1-007 (1) 502
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM atp2a1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    atp2a1 Contained in: [BAC] CH73-46H18 (1) (order this), CH211-11K18 (1) (order this)
    atp2a1 Contains: [SNP] rs3727695 (1), rs3727696 (1), rs3727697 (1), rs3727698 (1)
    atp2a1 Encodes: [EST] cb279 (1) (order this), cegs655 (1), fb17h11 (1), fb19b10 (1), fb39d07 (1), IMAGE:6910802 (1) (order this), IMAGE:7142105 (1) (order this)
    [cDNA] MGC:92110 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001007029 (1) 2985 bp
    Genomic GenBank:BX511232 171843 bp
    Select Tool
    Polypeptide UniProtKB:Q5U3A4 (1) 1005 aa
    Sequence Clusters UniGene:29167 (1)
    Sequence Information (all 27)
    OTHER atp2a1 GENE PAGES
  • Gene:260440 (1)
  • VEGA:OTTDARG00000032779 (1)
  • Ensembl(Zv9):ENSDARG00000020574 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish atp2a1 3  
    Human ATP2A1 16 (16p12.1)
  • OMIM:108730
  • Gene:487
  • Mouse Atp2a1 7 ( 69.04 cM)
  • MGI:105058
  • Gene:11937
  • Orthology Details
    CITATIONS (42)