ZFIN ID: ZDB-GENE-020905-1
Gene Name: ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
Gene Symbol: atp2a1
Previous Names: acc, accordion, cb279 (1), serca1 (1), serca (1), wu:cegs655, wu:fb17h11, wu:fb19b10, zgc:92110
Location: Chr: 3 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 38 figures from 10 publications
Directly Submitted Expression Data: 7 figures (15 images) from Rauch et al., 2003 [fb19b10]
  12 figures (21 images) from Rauch et al., 2003 [fb39d07]
  4 figures (7 images) from Thisse et al., 2001 [cb279]
  7 figures (22 images) from Rauch et al., 2003 [cegs655]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
  adaxial cell, eye, gill, mesoderm (all 12) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
dta5 Point Mutation ENU
mi25i Point Mutation ENU
mi289a Point Mutation ENU
sa10632 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa16659 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa17743 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tc249a Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • ti284a Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tm286 Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tn218b Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tp72x Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tq206 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • ty20 Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE
    Data: 13 figures from 4 publications
    Observed in: locomotion, mechanosensory behavior, musculoskeletal movement, neuromuscular process controlling balance (all 11) expand
    DISEASE ASSOCIATED WITH atp2a1 HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Brody myopathy Brody myopathy 601003
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process cellular calcium ion homeostasis (more)
    Cellular Component H zone (more)
    Molecular Function ATP binding (more)
    GO Terms (all 26)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001757 (1)
  • InterPro:IPR004014 (1)
  • InterPro:IPR005782 (1)
  • InterPro:IPR006068 (1)
  • InterPro:IPR008250 (1)
  • InterPro:IPR018303 (1)
  • InterPro:IPR023214 (1)
  • InterPro:IPR023298 (1)
  • InterPro:IPR023299 (1)
  • PROSITE:PS00154 (1)
  • Pfam:PF00122 (1)
  • Pfam:PF00689 (1)
  • Pfam:PF00690 (1)
  • Pfam:PF08282 (1)
  • EC:3.6.3.8 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA atp2a1-001 (1) 3390
    atp2a1-002 (1) 3311
    ncRNA atp2a1-003 (1) 520
    atp2a1-004 (1) 348
    mRNA atp2a1-005 (1) 416
    atp2a1-006 (1) 1049
    atp2a1-007 (1) 502
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM atp2a1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    atp2a1Contained in: [BAC] CH73-46H18 (1) (order this), CH211-11K18 (1) (order this)
    atp2a1Contains: [SNP] rs3727695 (1), rs3727696 (1), rs3727697 (1), rs3727698 (1)
    atp2a1Encodes: [EST] cb279 (1) (order this), cegs655 (1) (order this), fb17h11 (1), fb19b10 (1) (order this), fb39d07 (1) (order this), IMAGE:6910802 (1) (order this), IMAGE:7142105 (1) (order this)
    [cDNA] MGC:92110 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001007029 (1) 2985bp
    Genomic GenBank:BX511232 171843bp
    Select Tool
    Polypeptide UniProtKB:Q5U3A4 (1) 1005aa
    Sequence Clusters UniGene:29167 (1)
    Sequence Information (all 27)
    OTHER atp2a1 GENE PAGES 
  • Gene:260440 (1)
  • VEGA:OTTDARG00000032779 (1)
  • Ensembl(GRCz10):ENSDARG00000020574 (1)
  • ORTHOLOGY for atp2a1 (Chr: 3) 
    Species Symbol Chromosome Accession # Evidence
    Human ATP2A1 16
  • Gene:487
  • OMIM:108730
  • HGNC:811
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Mouse Atp2a1 7
  • MGI:105058
  • Gene:11937
  • Amino acid sequence comparison (1)
    Download Curated Orthology
    CITATIONS (44)