ZFIN ID: ZDB-GENE-020801-1
Gene Name: Bardet-Biedl syndrome 2
Gene Symbol: bbs2
Sequence Ontology ID : SO:0000704

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Previous Names: fb80a05, wu:fb80a05 (1)

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(Including Attributions)
Location: Chr: 18 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 8 figures from 2 publications
Directly Submitted Expression Data: 7 figures (11 images) from Thisse et al., 2004 [MGC:73041]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  retina, retinal photoreceptor layer, unspecified, whole organism
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa172 Point Mutation Unknown Premature Stop ENU
sa248 Point Mutation Unknown Premature Stop ENU
sa2952 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-bbs2 (1), MO2-bbs2 (1), MO3-bbs2 (1), MO4-bbs2 (1)
    PHENOTYPE
    Data: 5 figures from 3 publications
    Observed in: cell migration involved in gastrulation, convergent extension, gastrulation, notochord (all 8) expand
    DISEASE ASSOCIATED WITH bbs2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Bardet-Biedl syndrome 2 Bardet-Biedl syndrome 2 615981
    retinitis pigmentosa 74 Retinitis pigmentosa 74 616562
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process Kupffer's vesicle development (more)
    Cellular Component BBSome (more)
    GO Terms (all 19)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR015943 (1)
  • InterPro:IPR016616 (1)
  • InterPro:IPR017986 (1)
  • InterPro:IPR029333 (1)
  • InterPro:IPR029429 (1)
  • InterPro:IPR029430 (1)
  • Pfam:PF14781 (1)
  • Pfam:PF14782 (1)
  • Pfam:PF14783 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA bbs2-001 (1) 2577
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM bbs2 No data available
    MARKER RELATIONSHIPS
    bbs2Contained in: [BAC] DKEY-102F14 (1) (order this)
    bbs2Encodes: [EST] fb80a05 (1)
    [cDNA] MGC:73041 (1) (order this), MGC:86590 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_152887 (1) 2589bp
    Genomic GenBank:BX908765 (1) 155120bp
    Select Tool
    Polypeptide UniProtKB:Q6DI45 (1) 715aa
    Sequence Clusters UniGene:1599 (1)
    Sequence Information (all 20)
    OTHER bbs2 GENE PAGES
  • Alliance (1)
  • Gene:259187 (1)
  • VEGA:OTTDARG00000013018 (1)
  • Ensembl(GRCz10):ENSDARG00000041621 (1)
  • ORTHOLOGY for bbs2 (Chr: 18)
    CITATIONS (32)