ZFIN ID: ZDB-GENE-020708-4
Gene Name: thrombospondin 4b
Gene Symbol: thbs4b    Nomenclature History

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Previous Names: thbs4 (1), tsp4b (1), Tsp-4a (1), zgc:111910

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have calcium ion binding activity and growth factor activity. Involved in tendon development. Predicted to localize to collagen-containing extracellular matrix; extracellular space; and sarcoplasmic reticulum. Is expressed in musculature system; pectoral fin; and somite. Orthologous to human THBS4 (thrombospondin 4).
Genome Resources: Alliance (1),  Gene:252850 (1),  Ensembl(GRCz11):ENSDARG00000020072 (2)
GENE EXPRESSION
All Expression Data: 8 figures from 3 publications
Directly Submitted Expression Data: 6 figures (13 images) from Thisse et al., 2004 [MGC:111910]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa32331 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37222 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37223 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-thbs4b N/A 1
    DISEASE ASSOCIATED WITH thbs4b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH thbs4b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process tendon development (more)
    Cellular Component collagen-containing extracellular matrix (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA thbs4b-201 (1)    Ensembl 3397
    ncRNA thbs4b-002 (1)    Ensembl 822
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab3-thbs4b polyclonal IgG Rabbit IHC GeneTex
    3
    Ab1-thbs4b polyclonal Rabbit IHC 4
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM thbs4b No data available
    MARKER RELATIONSHIPS
    thbs4b Contained in: [Fosmid] CH1073-47C7 (1), CH1073-451F13 (1)
    thbs4b Encodes: [cDNA] MGC:111910 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_173226 (1) 3388 nt
    Genomic GenBank:CU466239 (1) 33935 nt
    Select Tool
    Polypeptide UniProtKB:F1R1P9 (1) 949 aa
    Sequence Information (all 16)
    ORTHOLOGY for thbs4b ( Chr: 21 )
    CITATIONS (30)