ZFIN ID: ZDB-GENE-020530-2
Gene Name: prostaglandin-endoperoxide synthase 2a
Gene Symbol: ptgs2a
Previous Names: Cox-2a (2), cox2 (1), ptgs2, fj02a10, unp1239, wu:fj02a10 (1), zCOX-2 (1)
Location: Chr: 2 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 17 figures from 13 publications
Wild-type Stages, Structures: Cleavage:16-cell (1.5h-1.75h) to Adult (90d-730d, breeding adult)
  brain, carotid artery, endoderm, eye (all 23) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
sa90 Unknown ENU
sa10104 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa11800 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa16633 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: CRISPR1-ptgs2a (1), MO1-ptgs2a (1), MO2-ptgs2a (1), MO3-ptgs2a (1), MO4-ptgs2a (1) (all 6) expand
    PHENOTYPE
    Data: 4 figures from 3 publications
    Observed in: brain ventricular system, cilium assembly, exocrine pancreas, hematopoietic stem cell (all 7) expand
    DISEASE ASSOCIATED WITH ptgs2a HUMAN ORTHOLOG No data available
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process cellular response to organic cyclic compound (more)
    Molecular Function peroxidase activity (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000742 (1)
  • InterPro:IPR010255 (1)
  • InterPro:IPR019791 (1)
  • InterPro:IPR029576 (1)
  • PROSITE:PS50026 (1)
  • PROSITE:PS50292 (1)
  • Pfam:PF03098 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ptgs2a-001 (1) 2135
    ncRNA ptgs2a-002 (1) 673
    GENE PRODUCT DESCRIPTION No description available
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ptgs2a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    ptgs2aContained in: [BAC] CH73-147D18 (1) (order this)
    ptgs2aContains: [SNP] rs3727618 (1), rs3727619 (1)
    ptgs2aEncodes: [EST] fj02a10 (1)
    [cDNA] MGC:66037 (1) (order this), MGC:77710 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_153657 (1) 2150bp
    Genomic GenBank:CU570979 (1) 105710bp
    Select Tool
    Polypeptide UniProtKB:Q6P4V3 (1) 601aa
    Sequence Clusters UniGene:113864 (1)
    Sequence Information (all 18)
    OTHER ptgs2a GENE PAGES 
  • Gene:246227 (1)
  • VEGA:OTTDARG00000034690 (1)
  • Ensembl(GRCz10):ENSDARG00000004539 (1)
  • ORTHOLOGY for ptgs2a (Chr: 2) 
    Species Symbol Chromosome Accession # Evidence
    Human PTGS2 1
  • Gene:5743
  • OMIM:600262
  • HGNC:9605
  • Amino acid sequence comparison (4)
    Conserved genome location (synteny) (3)
    Mouse Ptgs2 1
  • MGI:97798
  • Gene:19225
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (70)