Gene
ptgs1
- ID
- ZDB-GENE-020530-1
- Name
- prostaglandin-endoperoxide synthase 1
- Symbol
- ptgs1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Exhibits peroxidase activity and prostaglandin-endoperoxide synthase activity. Involved in animal organ development; cellular response to organic cyclic compound; and vasculogenesis. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is expressed in several structures, including cardiovascular system; digestive system; eye; mesoderm; and pleuroperitoneal region. Orthologous to human PTGS1 (prostaglandin-endoperoxide synthase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 18 figures from 14 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 12 figures from 7 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | EGF-like domain | Haem peroxidase, animal-type | Haem peroxidase domain superfamily, animal type | Haem peroxidase superfamily | Oxylipin biosynthesis and metabolism |
|---|---|---|---|---|---|---|
|
UniProtKB:Q8JH44
|
597 |
Interactions and Pathways
No data available
Plasmids
No data available