Gene

lmnb1

ID
ZDB-GENE-020424-2
Name
lamin B1
Symbol
lmnb1 Nomenclature History
Previous Names
  • fc06g01
  • wu:fc06g01 (1)
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to localize to intermediate filament. Human ortholog(s) of this gene implicated in adult-onset autosomal dominant demyelinating leukodystrophy. Orthologous to human LMNB1 (lamin B1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lmnb1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
adult-onset autosomal dominant demyelinating leukodystrophy Alliance Leukodystrophy, adult-onset, autosomal dominant 169500
Microcephaly 26, primary, autosomal dominant 619179
Associated With lmnb1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018039 Intermediate filament protein, conserved site
Domain IPR001322 Lamin tail domain
Domain IPR039008 Intermediate filament, rod domain
Homologous_superfamily IPR036415 Lamin tail domain superfamily
Domain Details Per Protein
Protein Length Intermediate filament protein, conserved site Intermediate filament, rod domain Lamin tail domain Lamin tail domain superfamily
UniProtKB:F1QHC4 588
UniProtKB:E9QCX6 329
UniProtKB:F1Q5F3 603
UniProtKB:Q6NUV5 587
UniProtKB:Q9PU57 588
UniProtKB:E9QIC9 157
UniProtKB:Q803N8 588
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations