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ZIRC
ZFIN ID: ZDB-GENE-020424-2
Gene Name: lamin B1
Gene Symbol: lmnb1
Sequence Ontology ID : SO:0001217

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Previous Names: fc06g01, wu:fc06g01 (1)

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(Including Attributions)
Location: Chr: 10 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have structural molecule activity. Predicted to localize to the intermediate filament. Human ortholog(s) of this gene implicated in adult-onset autosomal dominant demyelinating  ...
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55459]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa38787 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH lmnb1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    adult-onset autosomal dominant demyelinating leukodystrophy Leukodystrophy, adult-onset, autosomal dominant 169500
    DISEASE ASSOCIATED WITH lmnb1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component intermediate filament (more)
    GO Terms (all 1)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA lmnb1-004 (1) 796
    mRNA lmnb1-202 (1) 3021
    lmnb1-204 (1) 779
    lmnb1-205 (1) 1037
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lmnb1 No data available
    MARKER RELATIONSHIPS
    lmnb1 Contained in: [BAC] DKEY-184A18 (1) (order this)
    lmnb1 Encodes: [EST] fc06g01 (1)
    [cDNA] MGC:55459 (1) (order this), MGC:192857 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_152972 (1) 2994 bp
    Genomic GenBank:CR396586 (1) 225060 bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1Q5F3 (1) 603 aa
    Sequence Clusters UniGene:25051 (1)
    Sequence Information (all 27)
    ORTHOLOGY for lmnb1 ( Chr: 10 )
    CITATIONS (25)