ZFIN ID: ZDB-GENE-020419-7
Gene Name: chaperonin containing TCP1, subunit 7 (eta)
Gene Symbol: cct7    Nomenclature History

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Previous Names: chaperonin containing TCP1, subunit 7, chunp6934, etID46398.12 (1), etID46398.7 (1), fb38h02, fc05g05, wu:fb38h02 (1), wu:fc05g05 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have ATP binding activity and unfolded protein binding activity. Predicted to be involved in protein folding. Predicted to localize to the chaperonin-containing T-complex. Orthologous to human CCT7 (chaperonin containing TCP1 subunit 7).
Genome Resources: Alliance (1),  Gene:192324 (1),  Ensembl(GRCz11):ENSDARG00000007385 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu177]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi800aTg Transgenic Insertion Intron 1 Unknown DNA
hi2191Tg Transgenic Insertion Intron 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • hi3979Tg Transgenic Insertion Intron 1 Unknown DNA
    sa2381 Point Mutation Unknown Splice Site ENU
    sa21107 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21108 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE
    Data: 4 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH cct7 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cct7 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein folding (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Conserved_site IPR002194 Chaperonin TCP-1, conserved site
    Family IPR002423 Chaperonin Cpn60/TCP-1 family
    Family IPR012720 T-complex protein 1, eta subunit
    Family IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1)
    Homologous_superfamily IPR027409 GroEL-like apical domain superfamily
    Homologous_superfamily IPR027410 TCP-1-like chaperonin intermediate domain superfamily
    Homologous_superfamily IPR027413 GroEL-like equatorial domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cct7-201 (1)    Ensembl 2123
    ncRNA cct7-003 (1)    Ensembl 877
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cct7 No data available
    MARKER RELATIONSHIPS
    cct7 Contained in: [BAC] DKEYP-29G6 (1)
    cct7 Contains: [SNP] rs3728113 (1)
    cct7 Encodes: [EST] eu177 (1), fb38h02 (1), fc05g05 (1)
    [cDNA] MGC:195293 (1), MGC:195303 (1)
    cct7 Has Artifact: [EST] fa02g11
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_173248 (1) 2070 bp
    Genomic GenBank:BX511067 (1) 181406 bp
    Select Tool
    Polypeptide UniProtKB:B3DKJ0 (1) 547 aa
    Sequence Information (all 23)
    ORTHOLOGY for cct7 ( Chr: 7 )
    CITATIONS (37)