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ZIRC
ZFIN ID: ZDB-GENE-020419-36
Gene Name: actin-like 6A
Gene Symbol: actl6a    Nomenclature History

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Previous Names: baf53a (1), chunp6900, etID38198.6 (1), fb52e06, fl26e12, wu:fb52e06 (1), wu:fl26e12 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have chromatin binding activity. Predicted to be involved in chromatin organization; nervous system development; and regulation of transcription by RNA polymerase II. Predicted to localize to the NuA4 histone acetyltransferase complex and SWI/SNF complex. Is expressed in ventricular zone. Orthologous to human ACTL6A (actin like 6A).
Genome Resources: Alliance (1),  Gene:192313 (1),  Ensembl(GRCz11):ENSDARG00000070828 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:56056]
  7 figures (8 images) from Thisse et al., 2008 [MGC:56056]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi1072Tg Transgenic Insertion Exon 2 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la025482Tg Transgenic Insertion Unknown Unknown DNA
    sa8548 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40709 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-actl6a N/A 1
    PHENOTYPE
    Data: 2 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH actl6a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH actl6a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process ATP-dependent chromatin remodeling (more)
    Cellular Component NuA4 histone acetyltransferase complex (more)
    Molecular Function chromatin binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR004000 (1)
  • InterPro:IPR004001 (1)
  • PROSITE:PS00432 (1)
  • Pfam:PF00022 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA actl6a-201 (1)    Ensembl 1920
    ncRNA actl6a-002 (1) 549
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM actl6a No data available
    MARKER RELATIONSHIPS
    actl6a Contained in: [BAC] CH211-201H21 (1) (order this)
    actl6a Contains: [SNP] rs3727956 (1)
    actl6a Encodes: [EST] fb52e06 (1), fl26e12 (1)
    [cDNA] MGC:56056 (1) (order this), MGC:191760 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_173240 (1) 1820 bp
    Genomic GenBank:AL928701 (1) 188745 bp
    Select Tool
    Polypeptide UniProtKB:F1R473 (1) 429 aa
    Sequence Clusters UniGene:76448 (1)
    Sequence Information (all 26)
    ORTHOLOGY for actl6a ( Chr: 6 )
    CITATIONS (38)