ZFIN ID: ZDB-GENE-020419-23
Gene Name: ATPase H+ transporting V0 subunit ca
Gene Symbol: atp6v0ca    Nomenclature History

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Previous Names: atp6l, atp6v0c, cb993 (1), CHUNP6904, fb57d09, wu:fb57d09 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have proton-transporting ATPase activity, rotational mechanism. Involved in embryonic retina morphogenesis in camera-type eye; notochord cell vacuolation; and response to yeast. Predicted to localize to integral component of membrane. Is expressed in several structures, including digestive system; gonad; integument; nervous system; and unfertilized egg. Human ortholog(s) of this gene implicated in thyroid gland carcinoma. Orthologous to human ATP6V0C (ATPase H+ transporting V0 subunit c).
Genome Resources: Alliance (1),  Gene:192336 (1),  Ensembl(GRCz11):ENSDARG00000057853 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi1207Tg Transgenic Insertion Intron 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zf3063 Indel Unknown Unknown CRISPR
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-atp6v0ca 1
    MO1-atp6v0ca N/A 3
    MO2-atp6v0ca N/A 1
    MO3-atp6v0ca N/A 1
    DISEASE ASSOCIATED WITH atp6v0ca HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH atp6v0ca VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to yeast (more)
    Cellular Component integral component of membrane (more)
    Molecular Function proton transmembrane transporter activity (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA atp6v0ca-201 (1)    Ensembl 1522
    atp6v0ca-202 (1)    Ensembl 1237
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM atp6v0ca No data available
    MARKER RELATIONSHIPS
    atp6v0ca Contained in: [BAC] DKEY-81L17 (1) (order this)
    atp6v0ca Encodes: [BAC END] zk7n14
    [EST] cb993 (1) (order this), fb57d09 (order this)
    [STS] atp6l
    [cDNA] MGC:76969 (1), MGC:174785 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001105136 (1) 1550 nt
    Genomic GenBank:CR387933 (1) 182618 nt
    Select Tool
    Polypeptide UniProtKB:A7MCQ9 (1) 154 aa
    Sequence Information (all 22)
    ORTHOLOGY for atp6v0ca ( Chr: 3 )
    CITATIONS (47)