Gene
smc4
- ID
- ZDB-GENE-020419-21
- Name
- structural maintenance of chromosomes 4
- Symbol
- smc4 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be involved in mitotic chromosome condensation. Predicted to act upstream of or within chromosome condensation. Predicted to be located in chromosome and nucleus. Predicted to be part of condensin complex. Is expressed in several structures, including digestive system; nervous system; optic cup; otic vesicle; and pectoral fin. Orthologous to human SMC4 (structural maintenance of chromosomes 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb788 (8 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003395 | RecF/RecN/SMC, N-terminal |
| Domain | IPR010935 | SMCs flexible hinge |
| Family | IPR024704 | Structural maintenance of chromosomes protein |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036277 | SMCs flexible hinge superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | P-loop containing nucleoside triphosphate hydrolase | RecF/RecN/SMC, N-terminal | SMCs flexible hinge | SMCs flexible hinge superfamily | Structural maintenance of chromosomes protein |
|---|---|---|---|---|---|---|---|
| UniProtKB:E7FGC2 | InterPro | 1289 |
Interactions and Pathways
No data available
Plasmids
No data available