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ZIRC
ZFIN ID: ZDB-GENE-020416-2
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Gene Name: DCN1, defective in cullin neddylation 1, domain containing 2a
Gene Symbol: dcun1d2a    Nomenclature History

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Previous Names: cb191 (1), rp42-pen

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have cullin family protein binding activity; ubiquitin conjugating enzyme binding activity; and ubiquitin-like protein binding activity. Predicted to be involved in positive regulation of ubiquitin-protein transferase activity and protein neddylation. Predicted to localize to the ubiquitin ligase complex. Is expressed in several structures, including adaxial cell; axis; lens; pectoral fin; and pharyngeal arch 3-7 skeleton. Orthologous to human DCUN1D2 (defective in cullin neddylation 1 domain containing 2).
Genome Resources: Alliance (1),  Gene:192303 (1),  Ensembl(GRCz11):ENSDARG00000040838 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (8 images) from Thisse et al., 2001 [cb191]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la010782Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa13703 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dcun1d2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dcun1d2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of ubiquitin-protein transferase activity (more)
    Cellular Component ubiquitin ligase complex (more)
    Molecular Function cullin family protein binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR005176 (1)
  • InterPro:IPR009060 (1)
  • InterPro:IPR014764 (1)
  • InterPro:IPR042460 (1)
  • PROSITE:PS51229 (1)
  • Pfam:PF03556 (1)
    • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dcun1d2a-201 (1)    Ensembl 1654
    Select Tool
    dcun1d2a-202 (1)    Ensembl 791
    Select Tool
    dcun1d2a-203 (1)    Ensembl 728
    Select Tool
    dcun1d2a-204 (1)    Ensembl 910
    Select Tool
    Browsers: UCSC,  NCBI,  Ensembl,  ZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dcun1d2a No data available
    MARKER RELATIONSHIPS
    dcun1d2a Contained in: [BAC] CH211-160B11 (1) (order this)
    dcun1d2a Encodes: [EST] cb191 (1) (order this)
    [cDNA] MGC:77887 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_205538 (1) 1690 bp
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    Genomic GenBank:CR936415 (1) 91804 bp
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    Polypeptide UniProtKB:A0A2R8QJK6 (1) 270 aa
    Select Tool
    Sequence Clusters UniGene:12744 (1)
    Sequence Information (all 22)
    ORTHOLOGY for dcun1d2a ( Chr: 9 )
    CITATIONS (19)