ZFIN ID: ZDB-GENE-020402-2
Gene Name: glycine receptor, alpha 4b
Gene Symbol: glra4b    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Exhibits extracellularly glycine-gated ion channel activity. Predicted to contribute to extracellularly glycine-gated chloride channel activity and glycine binding activity. Predicted to be involved in several processes, including chloride transmembrane transport; glycinergic synaptic transmission; and neuropeptide signaling pathway. Predicted to localize to integral component of plasma membrane; neuron projection; and synapse. Is expressed in brain; hindbrain; retinal ganglion cell layer; retinal inner nuclear layer; and spinal cord. Orthologous to human GLRA4 (glycine receptor alpha 4 (pseudogene)).
Genome Resources: Alliance (1),  Gene:192125 (1),  Ensembl(GRCz11):ENSDARG00000058103 (1)
GENE EXPRESSION
All Expression Data: 6 figures from 4 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH glra4b HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH glra4b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process ion transmembrane transport (more)
Cellular Component integral component of membrane (more)
Molecular Function extracellularly glycine-gated ion channel activity (more)
GO Terms (all 25)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA glra4b-201 (1)    Ensembl 1926
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM glra4b No data available
MARKER RELATIONSHIPS
glra4b Contained in: [BAC] DKEY-103E21 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001202511 (1) 1924 nt
Genomic GenBank:BX470076 (1) 112637 nt
Select Tool
Polypeptide UniProtKB:F1QTT1 (1) 537 aa
Sequence Information (all 19)
ORTHOLOGY for glra4b ( Chr: 5 )
CITATIONS (28)