ZFIN ID: ZDB-GENE-020228-1
Gene Name: spinster homolog 1 (Drosophila)
Gene Symbol: spns1
Sequence Ontology ID : SO:0000704

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Previous Names: nrs (1), spinl, etID64740.3 (1), not really started, wu:fb95b12, wu:fi37e11 (1)

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(Including Attributions)
Location: Chr: 3 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Involved in autophagosome maturation and cellular senescence; predicted to localize to the integral component of membrane and mitochondrial inner membrane; orthologous to human SPNS1 (sphingolipid  ...
GENE EXPRESSION
Directly Submitted Expression Data: 7 figures (5 images) from Thisse et al., 2004 [MGC:55239]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi891Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40019 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 12 figures from 4 publications
    Observed in:
    DISEASE ASSOCIATED WITH spns1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH spns1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process autophagy (more)
    Cellular Component integral component of membrane (more)
    Molecular Function sphingolipid transporter activity (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR011701 (1)
  • InterPro:IPR020846 (1)
  • InterPro:IPR036259 (1)
  • PROSITE:PS50850 (1)
  • Pfam:PF07690 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA spns1-001 (1) 2593
    spns1-002 (1) 760
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM spns1 No data available
    MARKER RELATIONSHIPS
    spns1Contained in: [BAC] CH211-66P13 (1) (order this)
    spns1Contains: [SNP] rs3727685 (1), rs3727686 (1), rs3727687 (1), rs3727688 (1), rs3727689 (1)
    spns1Encodes: [EST] fb95b12 (1), fi37e11 (1)
    [cDNA] MGC:55239 (1) (order this), MGC:192713 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_153663 (1) 2643bp
    Genomic GenBank:BX784026 (1) 162371bp
    Select Tool
    Polypeptide UniProtKB:B2GSS2 (1) 506aa
    Sequence Clusters UniGene:76573 (1)
    Sequence Information (all 31)
    OTHER spns1 GENE PAGES
  • Alliance (1)
  • Gene:799873 (1)
  • VEGA:OTTDARG00000019686 (1)
  • ORTHOLOGY for spns1 (Chr: 3)
    CITATIONS (32)