Gene

mkrn1

ID
ZDB-GENE-020213-1
Name
makorin, ring finger protein, 1
Symbol
mkrn1 Nomenclature History
Previous Names
  • fl25h08
  • wu:fl25h08 (1)
  • zgc:110403
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to have ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Is expressed in several structures, including brain; eye; gonad; integument; and liver. Human ortholog(s) of this gene implicated in gonadal disease. Orthologous to several human genes including MKRN1 (makorin ring finger protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mkrn1 Human Ortholog
No data available
Associated With mkrn1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017907 Zinc finger, RING-type, conserved site
Domain IPR000571 Zinc finger, CCCH-type
Domain IPR001841 Zinc finger, RING-type
Domain IPR031644 E3 ubiquitin-protein ligase makorin 1, C-terminal
Domain IPR041367 E3 ligase, CCCH-type zinc finger
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily IPR036855 Zinc finger, CCCH-type superfamily
Domain Details Per Protein
Protein Length E3 ligase, CCCH-type zinc finger E3 ubiquitin-protein ligase makorin 1, C-terminal Zinc finger, CCCH-type Zinc finger, CCCH-type superfamily Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-type Zinc finger, RING-type, conserved site
UniProtKB:H0WEV7 236
UniProtKB:Q4VBT5 439
UniProtKB:H0WEB8 72
UniProtKB:B2GQH3 439
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations