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ZIRC
ZFIN ID: ZDB-GENE-020122-5
Gene Name: pbx/knotted 1 homeobox 1.1
Gene Symbol: pknox1.1
Sequence Ontology ID : SO:0000704

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Previous Names: prep1.1 (1), prep1, fc13f10, wu:fc13f10

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(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
AUTOMATED DESCRIPTION
Exhibits sequence-specific DNA binding activity. Involved in animal organ development and regulation of histone modification. Localizes to the cytoplasm and nucleus. Orthologous to human PKNOX1  ...
GENE EXPRESSION
All Expression Data: 5 figures from 5 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:66244]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa25422 Point Mutation Unknown Missense, Premature Stop ENU
sa34607 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH pknox1.1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pknox1.1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of histone methylation (more)
    Cellular Component cytoplasm (more)
    Molecular Function sequence-specific DNA binding (more)
    GO Terms (all 10)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA pknox1.1-201 (1) 2337
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM pknox1.1
    MARKER RELATIONSHIPS
    pknox1.1Contained in: [BAC] CH211-140M22 (1) (order this), DKEY-281I8 (1) (order this)
    pknox1.1Encodes: [EST] fc13f10 (1)
    [cDNA] MGC:66244 (1) (order this), MGC:174822 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131891 (1) 2332bp
    Genomic GenBank:BX294175 (1) 165355bp
    Select Tool
    Polypeptide UniProtKB:A9JRT3 (1) 433aa
    Sequence Clusters UniGene:78334 (1)
    Sequence Information (all 26)
    ORTHOLOGY for pknox1.1 (Chr: 9)
    CITATIONS (30)