ZFIN is now using GRCz12tu for Genomic Data
Gene
ptpra
- ID
- ZDB-GENE-020107-1
- Name
- protein tyrosine phosphatase receptor type A
- Symbol
- ptpra Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable protein tyrosine phosphatase activity. Involved in fin regeneration. Acts upstream of or within convergent extension involved in gastrulation; regulation of protein kinase activity; and retina development in camera-type eye. Predicted to be located in plasma membrane. Is expressed in blastomere; head; nervous system; and pectoral fin. Orthologous to human PTPRA (protein tyrosine phosphatase receptor type A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR016130 | Protein-tyrosine phosphatase, active site |
| Domain | IPR000242 | Tyrosine-specific protein phosphatase, PTPase domain |
| Domain | IPR000387 | Tyrosine-specific protein phosphatases domain |
| Domain | IPR003595 | Protein-tyrosine phosphatase, catalytic |
| Family | IPR016336 | Receptor tyrosine-protein phosphatase, alpha/epsilon-type |
| Family | IPR027262 | Receptor tyrosine-protein phosphatase alpha |
| Family | IPR050348 | Protein-Tyrosine Phosphatase |
| Homologous_superfamily | IPR029021 | Protein-tyrosine phosphatase-like |
Domain Details Per Protein
| Protein | Additional Resources | Length | Protein-Tyrosine Phosphatase | Protein-tyrosine phosphatase, active site | Protein-tyrosine phosphatase, catalytic | Protein-tyrosine phosphatase-like | Receptor tyrosine-protein phosphatase alpha | Receptor tyrosine-protein phosphatase, alpha/epsilon-type | Tyrosine-specific protein phosphatase, PTPase domain | Tyrosine-specific protein phosphatases domain |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:F1QE38 | InterPro | 831 | ||||||||
| UniProtKB:A0A8M9P361 | InterPro | 827 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers