ZFIN ID: ZDB-GENE-011205-8
Gene Name: NADH dehydrogenase 2, mitochondrial
Gene Symbol: mt-nd2    Nomenclature History

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Previous Names: mtnd2 (1), ND2 (1), cb950 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: MT Mapping Details/Browsers
Description: Predicted to have NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to localize to integral component of membrane; mitochondrial inner membrane; and respirasome. Is expressed in several structures, including digestive system; immature eye; midbrain; musculature system; and segmental plate. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; myocardial infarction; neurodegenerative disease (multiple); and urinary bladder cancer. Orthologous to human MT-ND2 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2).
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000063899 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH mt-nd2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH mt-nd2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process mitochondrial electron transport, NADH to ubiquinone (more)
Cellular Component integral component of membrane (more)
Molecular Function NADH dehydrogenase (ubiquinone) activity (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS No data available
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM mt-nd2 No data available
MARKER RELATIONSHIPS
mt-nd2 Encodes: [EST] cb950 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA GenBank:CF673273 (1) 668 nt
Genomic GenBank:AC024175 (1) 16596 nt
Polypeptide UniProtKB:Q9MIY9 (1) 348 aa
Sequence Information (all 5)
ORTHOLOGY for mt-nd2 ( Chr: MT )
CITATIONS (25)