ZFIN ID: ZDB-GENE-011128-9
Gene Name: guanylate cyclase 2D, retinal
Gene Symbol: gucy2d
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: gc3 (1), GUCY2d1 (1), RETGC-3 (1), zat, zatoichi

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have guanylate cyclase activity and peptide receptor activity; predicted to be involved in cGMP biosynthetic process and receptor guanylyl cyclase signaling pathway; predicted to  ...
GENE EXPRESSION
All Expression Data: 10 figures from 3 publications
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
s125 Unknown Unknown Unknown ENU
s376 Unknown Unknown Unknown ENU
sa16059 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20486 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 3 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH gucy2d HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    choroidal sclerosis ?Choroidal dystrophy, central areolar 1 215500
    cone-rod dystrophy 6 Cone-rod dystrophy 6 601777
    Leber congenital amaurosis 1 Leber congenital amaurosis 1 204000
    DISEASE ASSOCIATED WITH gucy2d VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cGMP biosynthetic process (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000719 (1)
  • InterPro:IPR001054 (1)
  • InterPro:IPR001245 (1)
  • InterPro:IPR001828 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR011645 (1)
  • InterPro:IPR018297 (1)
  • InterPro:IPR028082 (1)
  • InterPro:IPR029787 (1)
  • PROSITE:PS00452 (1)
  • PROSITE:PS50011 (1)
  • PROSITE:PS50125 (1)
  • Pfam:PF00211 (1)
  • Pfam:PF01094 (1)
  • Pfam:PF07701 (1)
  • Pfam:PF07714 (1)
  • EC:4.6.1.2 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA gucy2d-202 (1) 4522
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM gucy2d No data available
    MARKER RELATIONSHIPS
    gucy2dContained in: [BAC] CH211-284E13 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131866 (1) 3892bp
    Genomic GenBank:BX294181 (1) 171388bp
    Select Tool
    Polypeptide UniProtKB:A2BFQ0 (1) 1176aa
    Sequence Clusters UniGene:86944 (1)
    Sequence Information (all 21)
    OTHER gucy2d GENE PAGES
  • Alliance (1)
  • Gene:140426 (1)
  • VEGA:OTTDARG00000019027 (1)
  • ORTHOLOGY for gucy2d (Chr: 5)
    CITATIONS (27)