Gene

guca1b

ID

ZDB-GENE-011128-6

Name

guanylate cyclase activator 1B

Symbol

guca1b Nomenclature History

Previous Names

gcap2

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Exhibits calcium ion binding activity and calcium sensitive guanylate cyclase activator activity. Predicted to be involved in response to stimulus and visual perception. Is expressed in retina. Human ortholog(s) of this gene implicated in retinitis pigmentosa 48. Orthologous to human GUCA1B (guanylate cyclase activator 1B).

Genome Resources

Note

None

Expression

All Expression Data

5 figures from 3 publications

Cross-Species Comparison

High Throughput Data

No data available

Thisse Expression Data

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With guca1b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
retinitis pigmentosa 48	Alliance	Retinitis pigmentosa 48	613827

Associated With guca1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR018247	EF-Hand 1, calcium-binding site
Domain	IPR002048	EF-hand domain
Family	IPR015756	Guanylate cyclase activating protein 2
Family	IPR028846	Recoverin family
Homologous_superfamily	IPR011992	EF-hand domain pair