Gene

guca1b

ID
ZDB-GENE-011128-6
Name
guanylate cyclase activator 1B
Symbol
guca1b Nomenclature History
Previous Names
  • gcap2
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Exhibits calcium ion binding activity and calcium sensitive guanylate cyclase activator activity. Predicted to be involved in response to stimulus and visual perception. Is expressed in retina. Human ortholog(s) of this gene implicated in retinitis pigmentosa 48. Orthologous to human GUCA1B (guanylate cyclase activator 1B).
Genome Resources
Note
None
Expression
All Expression Data
5 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With guca1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
retinitis pigmentosa 48 Alliance Retinitis pigmentosa 48 613827
Associated With guca1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR018247 EF-Hand 1, calcium-binding site
Domain IPR002048 EF-hand domain
Family IPR015756 Guanylate cyclase activating protein 2
Family IPR028846 Recoverin family
Homologous_superfamily IPR011992 EF-hand domain pair
Domain Details Per Protein
Protein Length EF-Hand 1, calcium-binding site EF-hand domain EF-hand domain pair Guanylate cyclase activating protein 2 Recoverin family
UniProtKB:Q90WX3 197
UniProtKB:Q8UUY0 197
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations