Gene

gnat1

ID
ZDB-GENE-011128-11
Name
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
Symbol
gnat1 Nomenclature History
Previous Names
  • fk56e06
  • Galpha t1 (1)
  • transducin alpha (rod) (1)
  • wu:fk56e06 (1)
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway and response to light stimulus. Predicted to localize to heterotrimeric G-protein complex. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1G; congenital stationary night blindness autosomal dominant 3; and night blindness. Is expressed in pineal complex and visual system. Orthologous to human GNAT1 (G protein subunit alpha transducin 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
36 figures from 21 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gnat1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital stationary night blindness 1G Alliance Night blindness, congenital stationary, type 1G 616389
congenital stationary night blindness autosomal dominant 3 Alliance Night blindness, congenital stationary, autosomal dominant 3 610444
Associated With gnat1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit
Family IPR001408 G-protein alpha subunit, group I
Homologous_superfamily IPR011025 G protein alpha subunit, helical insertion
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length G-protein alpha subunit, group I G protein alpha subunit, helical insertion Guanine nucleotide binding protein (G-protein), alpha subunit P-loop containing nucleoside triphosphate hydrolase
UniProtKB:Q90WX6 350
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-gnat1 polyclonal IgG Rabbit
  • IHC
  • WB
ABclonal
8
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations