Gene

gnat1

ID
ZDB-GENE-011128-11
Name
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
Symbol
gnat1 Nomenclature History
Previous Names
  • fk56e06
  • Galpha t1 (1)
  • transducin alpha (rod) (1)
  • wu:fk56e06 (1)
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in G protein-coupled adenosine receptor signaling pathway; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; and response to light stimulus. Predicted to localize to heterotrimeric G-protein complex. Is expressed in pineal complex and visual system. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1G; congenital stationary night blindness autosomal dominant 3; and night blindness. Orthologous to human GNAT1 (G protein subunit alpha transducin 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
34 figures from 19 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gnat1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital stationary night blindness 1G Alliance Night blindness, congenital stationary, type 1G 616389
congenital stationary night blindness autosomal dominant 3 Alliance Night blindness, congenital stationary, autosomal dominant 3 610444
Associated With gnat1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit
Family IPR001408 G-protein alpha subunit, group I
Homologous_superfamily IPR011025 G protein alpha subunit, helical insertion
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length G-protein alpha subunit, group I G protein alpha subunit, helical insertion Guanine nucleotide binding protein (G-protein), alpha subunit P-loop containing nucleoside triphosphate hydrolase
UniProtKB:Q90WX6 350
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-gnat1 polyclonal IgG Rabbit
  • IHC
  • WB
ABclonal
7
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations