ZFIN ID: ZDB-GENE-011128-10
Gene Name: guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
Gene Symbol: gnat2
Previous Names: GNAT3 (1), nof, Galpha t2 (1), no optokinetic response f, T alpha C (1), Tc alpha (1), transducin alpha (cone) (1)
Location: Chr: 8 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 25 figures from 17 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
  epiphysis, eye, photoreceptor outer segment layer retinal cone cell, pineal complex (all 13) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
s377 Unknown Unknown Unknown ENU
sa41206 Point Mutation Unknown Unknown ENU
w21 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE
    Data: 2 figures from Phenotype Annotation (1994-2006)
    Observed in: eye, melanocyte, pigment cell, sensory system (all 6) expand
    DISEASE ASSOCIATED WITH gnat2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    achromatopsia Achromatopsia-4 613856
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process detection of light stimulus involved in visual perception (more)
    Cellular Component heterotrimeric G-protein complex (more)
    Molecular Function G-protein beta/gamma-subunit complex binding (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001019 (1)
  • InterPro:IPR001408 (1)
  • InterPro:IPR011025 (1)
  • InterPro:IPR027417 (1)
  • Pfam:PF00503 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA gnat2-001 (1) 2170
    gnat2-002 (1) 760
    ncRNA gnat2-003 (1) 630
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIES
    Ab3-gnat2 (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM gnat2
    Tg(-3.2gnat2:cacna2d4a-pHGFP), Tg(-3.2gnat2:EGFP), Tg(-3.2gnat2:GAL4-VP16,UAS:spHGFP), Tg(-3.2gnat2:GAP-CFP), Tg(-3.2gnat2:man2a1-GFP) (all 19) expand
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    gnat2Contained in: [BAC] CH211-77C7 (1) (order this)
    gnat2Encodes: [cDNA] MGC:73135 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131869 (1) 2126bp
    Genomic GenBank:CU462975 (1) 148505bp
    Select Tool
    Polypeptide UniProtKB:Q90WX5 (1) 354aa
    Sequence Clusters UniGene:81958 (1)
    Sequence Information (all 12)
    OTHER gnat2 GENE PAGES
  • Gene:140429 (1)
  • VEGA:OTTDARG00000028798 (1)
  • Ensembl(GRCz10):ENSDARG00000042529 (1)
  • ORTHOLOGY for gnat2 (Chr: 8)
    Species Symbol Chromosome Accession # Evidence
    Human GNAT2 1
  • Gene:2780
  • OMIM:139340
  • HGNC:4394
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Gnat2 3
  • MGI:95779
  • Gene:14686
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (67)