Gene

gpc4

ID
ZDB-GENE-011119-1
Name
glypican 4
Symbol
gpc4 Nomenclature History
Previous Names
  • gpc4/6
  • gpc6
  • chunp6920
  • fc47a08
  • fe05f10
  • kny (1)
  • knypek (1)
  • wu:fc47a08 (1)
  • wu:fe05f10 (1)
  • zgc:194854
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Involved in several processes, including gastrulation; post-anal tail morphogenesis; and skeletal system development. Predicted to localize to cell surface; extracellular region; and synapse. Is expressed in several structures, including axial chorda mesoderm; blastomere; lateral line system; quadrate-anguloarticular joint; and tail bud. Human ortholog(s) of this gene implicated in Keipert syndrome. Orthologous to human GPC4 (glypican 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
14 figures from 12 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
67 figures from 32 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gpc4 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Keipert syndrome Alliance Keipert syndrome 301026
Associated With gpc4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR001863 Glypican
Domain Details Per Protein
Protein Length Glypican
UniProtKB:B3DJ94 557
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA gpc4-201 (1) Havana 3998 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations