ZFIN ID: ZDB-GENE-011109-1
Gene Name: Kruppel-like factor 2a
Gene Symbol: klf2a
Sequence Ontology ID : SO:0000704

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Previous Names: etID35223.22 (1), fb08e06, wu:fb08e06 (1)

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(Including Attributions)
Location: Chr: 22 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits transcription regulatory region DNA binding activity; involved in several processes, including circulatory system development, nitric oxide biosynthetic process, and regulation of cell fate  ...
GENE EXPRESSION
All Expression Data: 33 figures from 24 publications
Wild-type Stages, Structures: Cleavage:64-cell (2.0h-2.25h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
bns11 Unknown Unknown Unknown TALEN
ig4 Indel Exon 1 Premature Stop TALEN
sa24120 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa30728 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sh317 Small Deletion Exon 2 Premature Stop TALEN
    Targeting reagents:
    PHENOTYPE
    Data: 12 figures from 7 publications
    Observed in:
    DISEASE ASSOCIATED WITH klf2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH klf2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process angiogenesis (more)
    Molecular Function transcription regulatory region DNA binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR013087 (1)
  • InterPro:IPR036236 (1)
  • PROSITE:PS00028 (1)
  • PROSITE:PS50157 (1)
  • Pfam:PF00096 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA klf2a-201 (1) 2180
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM klf2a
    MARKER RELATIONSHIPS
    klf2aContained in: [BAC] CH211-171D11 (1) (order this), DKEY-192M14 (1) (order this), DKEYP-70F9 (1)
    klf2aEncodes: [EST] fb08e06 (1)
    [cDNA] MGC:77570 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131856 (1) 2133bp
    Genomic GenBank:BX323550 (1) 200031bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q1LXI7 (1) 380aa
    Sequence Clusters UniGene:29173 (1)
    Sequence Information (all 17)
    OTHER klf2a GENE PAGES
  • Alliance (1)
  • Gene:117508 (1)
  • VEGA:OTTDARG00000012022 (1)
  • ORTHOLOGY for klf2a (Chr: 22)
    CITATIONS (74)