ZFIN ID: ZDB-GENE-011108-2
Gene Name: secreted frizzled-related protein 5
Gene Symbol: sfrp5    Nomenclature History

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Previous Names: sfrp1 (1), zgc:101849

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have Wnt-protein binding activity. Involved in several processes, including Wnt signaling pathway; animal organ development; and regulation of signal transduction. Predicted to localize to extracellular space. Is expressed in several structures, including anterior neural keel; anterior neural rod; gut; immature eye; and nervous system. Orthologous to human SFRP5 (secreted frizzled related protein 5).
Genome Resources: Alliance (1),  Gene:117510 (1),  Ensembl(GRCz11):ENSDARG00000039041 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa15896 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22366 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • wz08 Small Deletion Exon 1 Unknown CRISPR
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-sfrp5 1
    MO1-sfrp5 N/A 1
    MO2-sfrp5 N/A 1
    MO3-sfrp5 N/A 1
    DISEASE ASSOCIATED WITH sfrp5 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH sfrp5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process forebrain development (more)
    Cellular Component extracellular region (more)
    Molecular Function Wnt-protein binding (more)
    GO Terms (all 18)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA sfrp5-201 (1)    Ensembl 1976
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM sfrp5 No data available
    MARKER RELATIONSHIPS
    sfrp5 Contained in: [BAC] DKEY-285M9 (1) (order this)
    sfrp5 Encodes: [cDNA] MGC:101849 (1), MGC:191440 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131858 (1) 2006 nt
    Genomic GenBank:CU695206 (1) 75368 nt
    Select Tool
    Polypeptide UniProtKB:F1QJG6 (1) 310 aa
    Sequence Information (all 19)
    ORTHOLOGY for sfrp5 ( Chr: 13 )
    CITATIONS (37)