ZFIN ID: ZDB-GENE-011108-2
Gene Name: secreted frizzled-related protein 5
Gene Symbol: sfrp5
Sequence Ontology ID : SO:0000704

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Previous Names: sfrp1 (1), zgc:101849

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(Including Attributions)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 15 figures from 8 publications
Directly Submitted Expression Data: 6 figures (29 images) from Thisse et al., 2004 [MGC:101849]
Wild-type Stages, Structures: Gastrula:Shield (6.0h-8.0h) to Larval:Day 6 (144.0h-168.0h)
  anterior neural keel, anterior neural plate, anterior neural rod, anterior neural tube (all 46) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa15896 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa22366 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • wz08 Small Deletion Exon 1 Unknown CRISPR
    Targeting reagents: CRISPR1-sfrp5 (1), MO1-sfrp5 (1), MO2-sfrp5 (1), MO3-sfrp5 (1)
    PHENOTYPE
    Data: 3 figures from Stuckenholz et al., 2013
    Observed in: endoderm, hepatoblast, intestine, liver (all 5) expand
    DISEASE ASSOCIATED WITH sfrp5 HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process forebrain development (more)
    Cellular Component extracellular region (more)
    Molecular Function G-protein coupled receptor activity (more)
    GO Terms (all 20)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001134 (1)
  • InterPro:IPR008993 (1)
  • InterPro:IPR015526 (1)
  • InterPro:IPR018933 (1)
  • InterPro:IPR020067 (1)
  • InterPro:IPR034860 (1)
  • InterPro:IPR036790 (1)
  • PROSITE:PS50038 (1)
  • PROSITE:PS50189 (1)
  • Pfam:PF01392 (1)
  • Pfam:PF01759 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA sfrp5-001 (1) 1976
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM sfrp5 No data available
    MARKER RELATIONSHIPS
    sfrp5Contained in: [BAC] DKEY-285M9 (1) (order this)
    sfrp5Encodes: [cDNA] MGC:101849 (1) (order this), MGC:191440 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131858 (1) 2006bp
    Genomic GenBank:CU695206 (1) 75368bp
    Select Tool
    Polypeptide UniProtKB:F1QJG6 (1) 310aa
    Sequence Clusters UniGene:151871 (1)
    Sequence Information (all 22)
    OTHER sfrp5 GENE PAGES
  • Alliance (1)
  • Gene:117510 (1)
  • VEGA:OTTDARG00000035464 (1)
  • Ensembl(GRCz10):ENSDARG00000039041 (1)
  • ORTHOLOGY for sfrp5 (Chr: 13)
    CITATIONS (32)