Gene
ednraa
- ID
- ZDB-GENE-010906-2
- Name
- endothelin receptor type Aa
- Symbol
- ednraa Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable endothelin receptor activity. Acts upstream of with a positive effect on developmental pigmentation. Acts upstream of or within cartilage development; regulation of proton transport; and social behavior. Predicted to be located in plasma membrane. Is expressed in several structures, including epithelium; forebrain; neural crest; pharyngeal arch; and vasculature. Human ortholog(s) of this gene implicated in hypertension (multiple); lung disease; mandibulofacial dysostosis with alopecia; migraine; and obstructive sleep apnea. Orthologous to human EDNRA (endothelin receptor type A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 20 figures from 5 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Endothelin receptor A | Endothelin receptor family | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|---|
|
UniProtKB:B8JIH1
|
24 | ||||
|
UniProtKB:A5JV23
|
422 | ||||
|
UniProtKB:A0A0B5JFE8
|
93 | ||||
|
UniProtKB:B3DLG5
|
422 | ||||
|
UniProtKB:Q90YB8
|
168 | ||||
|
UniProtKB:B3DGY2
|
422 | ||||
|
UniProtKB:D0MQ51
|
411 |
| Type | Name | Length (nt) | Analysis |
|---|---|---|---|
| mRNA |
ednraa-201
(1)
|
2665 nt | |
| mRNA |
ednraa-203
(1)
|
200 nt | |
| ncRNA |
ednraa-003
(1)
|
391 nt |
Interactions and Pathways
No data available
Plasmids
No data available