ZFIN ID: ZDB-GENE-010822-2
Gene Name: neural cell adhesion molecule 1b
Gene Symbol: ncam1b    Nomenclature History

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Previous Names: ncam3, zPCAM (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Involved in axon guidance. Predicted to localize to the integral component of membrane. Human ortholog(s) of this gene implicated in bipolar disorder and pancreatic cancer. Is expressed in nervous system; otic vesicle; posterior neural keel; spinal cord neural rod; and spinal cord neural tube. Orthologous to human NCAM1 (neural cell adhesion molecule 1).
Genome Resources: Alliance (1),  Gene:114442 (1),  Ensembl(GRCz11):ENSDARG00000007220 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la019186Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la019189Tg Transgenic Insertion Unknown Unknown DNA
    sa35854 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35855 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42522 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ncam1b N/A 1
    MO2-ncam1b N/A 1
    DISEASE ASSOCIATED WITH ncam1b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ncam1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process axon guidance (more)
    Cellular Component integral component of membrane (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR003598 Immunoglobulin subtype 2
    Domain IPR003599 Immunoglobulin subtype
    Domain IPR003961 Fibronectin type III
    Domain IPR007110 Immunoglobulin-like domain
    Domain IPR013098 Immunoglobulin I-set
    Family IPR009138 Neural cell adhesion
    Family IPR033019 Neural cell adhesion molecule 1
    Homologous_superfamily IPR013783 Immunoglobulin-like fold
    Homologous_superfamily IPR036116 Fibronectin type III superfamily
    Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ncam1b-202 (1)    Ensembl 961
    ncam1b-203 (1)    Ensembl 3738
    ncam1b-204 (1)    Ensembl 812
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-ncam1b polyclonal Rabbit IHC 2
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ncam1b No data available
    MARKER RELATIONSHIPS
    ncam1b Contained in: [BAC] DKEY-78D3 (1) (order this), DKEY-85H21 (1) (order this)
    ncam1b Encodes: [cDNA] cssl:d097 (1), cssl:d825 (1), MGC:193517 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131831 (1) 3738 nt
    Genomic GenBank:CR626905 (1) 201465 nt Blast at MegaBLAST
    Polypeptide UniProtKB:E9QJ12 (1) 1031 aa
    Sequence Information (all 65)
    ORTHOLOGY for ncam1b ( Chr: 15 )
    CITATIONS (40)