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ZIRC
ZFIN ID: ZDB-GENE-010817-3
Gene Name: angiopoietin-like 3
Gene Symbol: angptl3
Sequence Ontology ID : SO:0001217

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Previous Names: fb60e11, fb66h02, wu:fb60e11 (1), wu:fb66h02

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(Including Attributions)
Location: Chr: 6 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Involved in hepatocyte proliferation and lipid metabolic process. Human ortholog(s) of this gene implicated in familial hypobetalipoproteinemia 2. Is expressed in liver; liver primordium; and yolk  ...
GENE EXPRESSION
All Expression Data: 8 figures from 2 publications
Directly Submitted Expression Data: 7 figures (12 images) from Thisse et al., 2005 [eu543]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents:
DISEASE ASSOCIATED WITH angptl3 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
familial hypobetalipoproteinemia 2 Hypobetalipoproteinemia, familial, 2 605019
DISEASE ASSOCIATED WITH angptl3 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process hepatocyte proliferation (more)
GO Terms (all 3)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002181 (1)
  • InterPro:IPR036056 (1)
  • PROSITE:PS51406 (1)
  • Pfam:PF00147 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA angptl3-201 (1) 2539
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM angptl3 No data available
    MARKER RELATIONSHIPS
    angptl3 Contained in: [BAC] CH211-208A5 (1) (order this)
    angptl3 Encodes: [EST] eu543 (1), fb60e11 (1), fb66h02
    [cDNA] MGC:194823 (1)
    angptl3 Has Artifact: [cDNA] MGC:111943 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131818 (1) 1385 bp
    Genomic GenBank:BX936431 (1) 127584 bp
    Select Tool
    Polypeptide UniProtKB:F1QYL5 (1) 466 aa
    Sequence Clusters UniGene:3332 (1)
    Sequence Information (all 25)
    ORTHOLOGY for angptl3 ( Chr: 6 )
    CITATIONS (23)