Gene

angptl3

ID
ZDB-GENE-010817-3
Name
angiopoietin-like 3
Symbol
angptl3 Nomenclature History
Previous Names
  • fb60e11
  • fb66h02
  • wu:fb60e11 (1)
  • wu:fb66h02
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Involved in hepatocyte proliferation and lipid metabolic process. Human ortholog(s) of this gene implicated in familial hypobetalipoproteinemia 2. Is expressed in liver; liver primordium; and yolk syncytial layer. Orthologous to human ANGPTL3 (angiopoietin like 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Lee et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With angptl3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
familial hypobetalipoproteinemia 2 Alliance Hypobetalipoproteinemia, familial, 2 605019
Associated With angptl3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
Homologous_superfamily IPR014716 Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1
Homologous_superfamily IPR036056 Fibrinogen-like, C-terminal
Domain Details Per Protein
Protein Length Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 Fibrinogen-like, C-terminal
UniProtKB:Q90Z17 458
UniProtKB:B3DID4 464
UniProtKB:F1QYL5 466
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations