ZFIN ID: ZDB-GENE-010730-1
Gene Name: BCL2 like 1
Gene Symbol: bcl2l1
Sequence Ontology ID : SO:0000704

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Previous Names: bcl-XL (1), bcl2l, cb1021 (1), zfBLP1 (1)

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(Including Attributions)
Location: Chr: 23 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits cysteine-type endopeptidase inhibitor activity involved in apoptotic process; involved in several processes, including negative regulation of apoptotic process, thyroid gland development,  ...
GENE EXPRESSION
All Expression Data: 19 figures from 12 publications
Directly Submitted Expression Data: 5 figures (10 images) from Thisse et al., 2001 [cb1021]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:6910760]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la010762Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15253 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 3 figures from Porreca et al., 2012
    Observed in:
    DISEASE ASSOCIATED WITH bcl2l1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH bcl2l1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of apoptotic process (more)
    Cellular Component integral component of membrane (more)
    Molecular Function cysteine-type endopeptidase inhibitor activity involved in apoptotic process (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002475 (1)
  • InterPro:IPR003093 (1)
  • InterPro:IPR013279 (1)
  • InterPro:IPR020717 (1)
  • InterPro:IPR026298 (1)
  • InterPro:IPR036834 (1)
  • PROSITE:PS01080 (1)
  • PROSITE:PS50062 (1)
  • PROSITE:PS50063 (1)
  • Pfam:PF00452 (1)
  • Pfam:PF02180 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA bcl2l1-003 (1) 1989
    mRNA bcl2l1-201 (1) 2025
    bcl2l1-202 (1) 1979
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM bcl2l1
    MARKER RELATIONSHIPS
    bcl2l1Contained in: [BAC] DKEY-192I18 (1) (order this)
    bcl2l1Encodes: [EST] cb1021 (1) (order this), IMAGE:6910760 (1) (order this)
    [cDNA] MGC:55232 (1) (order this), MGC:86578 (1) (order this), MGC:192331 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131807 (1) 1942bp
    Genomic GenBank:CR788311 (1) 147664bp
    Select Tool
    Polypeptide UniProtKB:Q90Z98 (1) 238aa
    Sequence Clusters UniGene:79623 (1)
    Sequence Information (all 24)
    OTHER bcl2l1 GENE PAGES
  • Alliance (1)
  • Gene:114401 (1)
  • VEGA:OTTDARG00000028128 (1)
  • Ensembl(GRCz11):ENSDARG00000008434 (2)
  • ORTHOLOGY for bcl2l1 (Chr: 23)
    CITATIONS (76)