ZFIN Gene: etv6

ZFIN ID: ZDB-GENE-010727-1

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Gene Name:	ets variant 6
Gene Symbol:	etv6
Previous Names:	id:ibd2308, ztel (1)
Location:	Chr: 4 Mapping Details/Browsers
Nomenclature History

Gene Name:

ets variant 6

Gene Symbol:

etv6

Previous Names:

id:ibd2308, ztel (1)

Location:

Chr: 4 Mapping Details/Browsers

Nomenclature History

GENE EXPRESSION
All Expression Data:	7 figures from 4 publications
Directly Submitted Expression Data:	1 figure (1 image) from Thisse et al., 2004 [MGC:55785]
	4 figures (6 images) from Kudoh et al., 2001 [ibd2308]
Wild-type Stages, Structures:	Zygote:1-cell (0.0h-0.75h) to Larval:Day 6 (144.0h-168.0h)
	anterior lateral mesoderm , anterior lateral mesoderm cell , blood island , brain (all 21)
Curated Microarray Expression:	GEO (1)

GENE EXPRESSION

All Expression Data:

7 figures from 4 publications

Directly Submitted Expression Data:

1 figure (1 image) from Thisse et al., 2004 [MGC:55785]

4 figures (6 images) from Kudoh et al., 2001 [ibd2308]

Wild-type Stages, Structures:

Zygote:1-cell (0.0h-0.75h) to Larval:Day 6 (144.0h-168.0h)

anterior lateral mesoderm, anterior lateral mesoderm cell, blood island, brain (all 21) expand

Curated Microarray Expression:

GEO (1)

DISEASE ASSOCIATED WITH etv6 HUMAN ORTHOLOG

Disease Ontology Term	OMIM Term	OMIM Phenotype ID
acute myeloid leukemia	Leukemia, acute myeloid, somatic	601626
	Thrombocytopenia 5	616216

GENE ONTOLOGY

Ontology	GO Term
Biological Process	embryonic hemopoiesis (more)
Cellular Component	nucleus (more)
Molecular Function	DNA binding (more)

GO Terms (all 6)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR000418 (1) InterPro:IPR003118 (1) InterPro:IPR011991 (1) InterPro:IPR013761 (1)	PROSITE:PS00346 (1) PROSITE:PS50061 (1) PROSITE:PS51433 (1)	Pfam:PF00178 (1) Pfam:PF02198 (1)

SEGMENT (CLONE AND PROBE) RELATIONSHIPS

etv6Encodes:

[EST] ibd2308 (order this)
[cDNA] MGC:55785 (1) (order this), MGC:77384 (1) (order this), MGC:192902 (1) (order this)

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_131832 (1)	1945bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega
Polypeptide	UniProtKB:B2GTA2 (1)	444aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast Vega Protein Blast
Sequence Clusters	UniGene:10306 (1)

Type

Accession #

Length (bp/aa)

Analysis

RNA

RefSeq:NM_131832 (1)

1945bp

Select Tool

ZFIN BLAST

NCBI BLAST

Ensembl

UCSC BLAT

Vega

Polypeptide

UniProtKB:B2GTA2 (1)

444aa

Select Tool

ZFIN BLAST

SIB BLAST

Ensembl Protein Blast

Vega Protein Blast

Sequence Clusters

UniGene:10306 (1)

ORTHOLOGY for etv6 (Chr: 4)

Species	Symbol	Chromosome	Accession #	Evidence
Human	ETV6	12	Gene:2120 OMIM:600618 HGNC:3495	Amino acid sequence comparison (2) Phylogenetic tree (1)
Mouse	Etv6	6	MGI:109336 Gene:14011	Amino acid sequence comparison (2) Phylogenetic tree (1)

Download Curated Orthology

Data:	6 figures from Rasighaemi et al., 2014
Observed in:	blood cell , common lymphoid progenitor , erythroblast , hematopoietic stem cell (all 13)