ZFIN ID: ZDB-GENE-010727-1
Gene Name: ets variant 6
Gene Symbol: etv6
Previous Names: id:ibd2308, ztel (1)
Location: Chr: 4   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 6 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55785]
  4 figures (6 images) from Kudoh et al., 2001 [ibd2308]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
  blood island, brain, epiblast, hypoblast (all 7) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Knockdown reagents: MO1-etv6 (1), MO2-etv6 (1)
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Leukemia, acute myeloid, somatic 601626
Thrombocytopenia 5 616216
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of transcription, DNA-templated (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000418 (1)
  • InterPro:IPR003118 (1)
  • InterPro:IPR011991 (1)
  • InterPro:IPR013761 (1)
  • PROSITE:PS00346 (1)
  • PROSITE:PS50061 (1)
  • PROSITE:PS51433 (1)
  • Pfam:PF00178 (1)
  • Pfam:PF02198 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM etv6 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    etv6 Encodes: [EST] ibd2308 (order this)
    [cDNA] MGC:55785 (1) (order this), MGC:77384 (1) (order this), MGC:192902 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131832 (1) 1945 bp
    Genomic RefSeq:NW_003337254 (1) 10603 bp Blast at Vega
    Polypeptide UniProtKB:B2GTA2 (1) 444 aa
    Sequence Clusters UniGene:10306 (1)
    Sequence Information (all 26)
    OTHER etv6 GENE PAGES
  • Gene:114444 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA
    Zebrafish etv6 4  
    Human ETV6 12 (12p13)
  • OMIM:600618
  • Gene:2120
  • Mouse Etv6 6 ( 64.58 cM)
  • MGI:109336
  • Gene:14011
  • Orthology Details
    CITATIONS (18)