ZFIN ID: ZDB-GENE-010726-1
Gene Name: B-cell translocation gene 1, anti-proliferative
Gene Symbol: btg1    Nomenclature History

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Previous Names: btg-a (1), sb:cb1010, wu:fb14h05, wu:fb40c11, wu:fk92d10, zgc:65815 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Predicted to be involved in negative regulation of cell population proliferation and negative regulation of mitotic cell cycle. Predicted to localize to the cytoplasm and nucleus. Is expressed in several structures, including cardiovascular system; ectoderm; mesoderm; nervous system; and neural tube. Orthologous to human BTG1 (BTG anti-proliferation factor 1).
Genome Resources: Alliance (1),  Gene:114432 (1),  Ensembl(GRCz11):ENSDARG00000027249 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa12374 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH btg1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH btg1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of cell population proliferation (more)
    Cellular Component cytoplasm (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR002087 Anti-proliferative protein
    Homologous_superfamily IPR036054 BTG-like domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA btg1-201 (1)    Ensembl 3627
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM btg1 No data available
    MARKER RELATIONSHIPS
    btg1 Contained in: [BAC] CH211-272H10 (1)
    btg1 Encodes: [EST] cb1010 (1) (order this), fb14h05, fb40c11 (1), fk92d10 (1)
    [cDNA] MGC:65815 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200020 (1) 1490 bp
    Genomic GenBank:BX255893 (1) 99176 bp
    Select Tool
    Polypeptide UniProtKB:Q6PH73 (1) 182 aa
    Sequence Information (all 16)
    ORTHOLOGY for btg1 ( Chr: 4 )
    CITATIONS (23)