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ZIRC
ZFIN ID: ZDB-GENE-010724-4
Gene Name: myelin protein zero
Gene Symbol: mpz
Sequence Ontology ID : SO:0001217

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Previous Names: p0, sc:d0186, wu:fc04b11, wu:fi30g06, zgc:103775

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(Including Attributions)
Location: Chr: 2 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Localizes to the myelin sheath. Human ortholog(s) of this gene implicated in neuromuscular disease (multiple). Is expressed in several structures, including Rohon-Beard neurons; basal plate midbrain  ...
GENE EXPRESSION
All Expression Data: 35 figures from 17 publications
Directly Submitted Expression Data: 7 figures (15 images) from Thisse et al., 2004 [MGC:103775]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa62 Point Mutation Unknown Premature Stop ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH mpz HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Charcot-Marie-Tooth disease dominant intermediate D Charcot-Marie-Tooth disease, dominant intermediate D 607791
Charcot-Marie-Tooth disease type 1B Charcot-Marie-Tooth disease, type 1B 118200
Charcot-Marie-Tooth disease type 2I Charcot-Marie-Tooth disease, type 2I 607677
Charcot-Marie-Tooth disease type 2J Charcot-Marie-Tooth disease, type 2J 607736
Charcot-Marie-Tooth disease type 3 Dejerine-Sottas disease 145900
Hypomyelinating neuropathy, congenital, 2 618184
Roussy-Levy syndrome 180800
DISEASE ASSOCIATED WITH mpz VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Cellular Component myelin sheath (more)
GO Terms (all 4)
TRANSCRIPTS
Type Name Length (bp) Analysis
ncRNA mpz-002 (1) 598
mRNA mpz-202 (1) 2344
mpz-203 (1) 1389
mpz-204 (1) 943
GENE PRODUCT DESCRIPTION No description available
INTERACTIONS AND PATHWAYS
ANTIBODIES
PLASMIDS No data available
MARKER RELATIONSHIPS
mpz Contained in: [BAC] DKEYP-35B8 (1)
mpz Contains: [SNP] rs3727652 (1)
mpz Encodes: [EST] fc04b11 (1), fi30g06 (1)
[cDNA] cssl:d186 (1), cssl:d806 (1), MGC:103775 (1) (order this), MGC:191219 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_194361 (1) 2339 bp
Genomic GenBank:BX294126 (1) 179476 bp
Select Tool
Polypeptide UniProtKB:A0A2R8QN30 (1) 228 aa
Sequence Clusters UniGene:78005 (1)
Sequence Information (all 52)
ORTHOLOGY for mpz ( Chr: 2 )
CITATIONS (56)