ZFIN ID: ZDB-GENE-010724-2
Gene Name: calpain 9
Gene Symbol: capn9    Nomenclature History

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Previous Names: cb545 (1), fb77d06, wu:fb77d06, zgc:92451

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to the cytoplasm. Human ortholog(s) of this gene implicated in stomach cancer. Is expressed in EVL; epidermis; periderm; peripheral olfactory organ; and pharynx. Orthologous to human CAPN9 (calpain 9).
Genome Resources: Alliance (1),  Gene:445107 (1),  Ensembl(GRCz11):ENSDARG00000012341 (2)
GENE EXPRESSION
All Expression Data: 16 figures from 5 publications
Directly Submitted Expression Data: 6 figures (15 images) from Thisse et al., 2001 [cb545]
  6 figures (6 images) from Thisse et al., 2004 [IMAGE:7152126]
Wild-type Stages, Structures: Blastula:30%-epiboly (4.66h-5.25h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa25682 Point Mutation Unknown Splice Site ENU
sa39702 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko1072a Small Deletion Unknown Unknown CRISPR
    zko1072b Small Deletion Unknown Unknown CRISPR
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-capn9 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH capn9 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH capn9 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process digestion (more)
    Cellular Component cytoplasm (more)
    Molecular Function calcium-dependent cysteine-type endopeptidase activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Active_site IPR000169 Cysteine peptidase, cysteine active site
    Binding_site IPR018247 EF-Hand 1, calcium-binding site
    Domain IPR001300 Peptidase C2, calpain, catalytic domain
    Domain IPR002048 EF-hand domain
    Domain IPR022682 Peptidase C2, calpain, large subunit, domain III
    Domain IPR022683 Peptidase C2, calpain, domain III
    Domain IPR033883 Calpain subdomain III
    Family IPR022684 Peptidase C2, calpain family
    Family IPR029543 Calpain-8
    Homologous_superfamily IPR011992 EF-hand domain pair
    Homologous_superfamily IPR036213 Calpain large subunit, domain III superfamily
    Homologous_superfamily IPR038765 Papain-like cysteine peptidase superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA capn9-201 (1)    Ensembl 2668
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM capn9 No data available
    MARKER RELATIONSHIPS
    capn9 Contained in: [BAC] CH73-59B17 (1), CH211-52O18 (1)
    capn9 Encodes: [EST] cb545 (1) (order this), fb77d06 (1), IMAGE:7152126 (1)
    [cDNA] MGC:92451 (1), MGC:193080 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001003501 (1) 2645 nt
    Genomic GenBank:FP017162 (1) 76731 nt
    Select Tool
    Polypeptide UniProtKB:F1RCJ4 (1) 688 aa
    Sequence Information (all 18)
    ORTHOLOGY for capn9 ( Chr: 1 )
    CITATIONS (28)