Gene

dusp5

ID
ZDB-GENE-010625-1
Name
dual specificity phosphatase 5
Symbol
dusp5 Nomenclature History
Previous Names
  • wu:fc03b11
  • wu:fc86e02
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have MAP kinase tyrosine/serine/threonine phosphatase activity; mitogen-activated protein kinase binding activity; and protein tyrosine/threonine phosphatase activity. Predicted to be involved in endoderm formation; inactivation of MAPK activity; and protein dephosphorylation. Predicted to localize to cytoplasm and nucleus. Is expressed in several structures, including angioblastic mesenchymal cell; brain; intermediate cell mass of mesoderm; mesoderm; and vasculature. Orthologous to human DUSP5 (dual specificity phosphatase 5).
Genome Resources
Note
None
Expression
All Expression Data
16 figures from 8 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dusp5 Human Ortholog
No data available
Associated With dusp5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR016130 Protein-tyrosine phosphatase, active site
Domain IPR000387 Tyrosine specific protein phosphatases domain
Domain IPR001763 Rhodanese-like domain
Domain IPR003595 Protein-tyrosine phosphatase, catalytic
Domain IPR020422 Dual specificity protein phosphatase domain
Family IPR008343 Mitogen-activated protein (MAP) kinase phosphatase
Homologous_superfamily IPR029021 Protein-tyrosine phosphatase-like
Homologous_superfamily IPR036873 Rhodanese-like domain superfamily
Domain Details Per Protein
Protein Length Dual specificity protein phosphatase domain Mitogen-activated protein (MAP) kinase phosphatase Protein-tyrosine phosphatase, active site Protein-tyrosine phosphatase, catalytic Protein-tyrosine phosphatase-like Rhodanese-like domain Rhodanese-like domain superfamily Tyrosine specific protein phosphatases domain
UniProtKB:Q6PBT4 368
UniProtKB:Q535D8 341
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations