Gene
neurod2
- ID
- ZDB-GENE-010608-3
- Name
- neuronal differentiation 2
- Symbol
- neurod2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in neuron differentiation and regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in granule cell. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy. Orthologous to human NEUROD2 (neuronal differentiation 2).
- Genome Resources
- Note
- None
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
developmental and epileptic encephalopathy 72 | Alliance | Developmental and epileptic encephalopathy 72 | 618374 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
Domain | IPR022575 | Neurogenic differentiation factor, domain of unknown function |
Family | IPR016637 | Neurogenic differentiation factor NeuroD |
Family | IPR032649 | Neurogenic differentiation factor 2 |
Homologous_superfamily | IPR036638 | Helix-loop-helix DNA-binding domain superfamily |
Domain Details Per Protein
Protein | Length | Helix-loop-helix DNA-binding domain superfamily | Myc-type, basic helix-loop-helix (bHLH) domain | Neurogenic differentiation factor 2 | Neurogenic differentiation factor, domain of unknown function | Neurogenic differentiation factor NeuroD |
---|---|---|---|---|---|---|
UniProtKB:Q9W6C8
|
363 | |||||
UniProtKB:B3DFQ6
|
363 |
Type | Name | Length (nt) | Analysis |
---|---|---|---|
mRNA |
neurod2-201
(1)
|
1604 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Gene Tree
- Ensembl