Gene

neurod2

ID
ZDB-GENE-010608-3
Name
neuronal differentiation 2
Symbol
neurod2 Nomenclature History
Previous Names
  • ndr2 (1)
  • fj49a11
  • NDF2 (1)
  • wu:fj49a11
  • zNdr2 (1)
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in neuron differentiation and regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in granule cell. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy. Orthologous to human NEUROD2 (neuronal differentiation 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With neurod2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
developmental and epileptic encephalopathy 72 Alliance Developmental and epileptic encephalopathy 72 618374
Associated With neurod2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Domain IPR022575 Neurogenic differentiation factor, domain of unknown function
Family IPR016637 Neurogenic differentiation factor NeuroD
Family IPR032649 Neurogenic differentiation factor 2
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Helix-loop-helix DNA-binding domain superfamily Myc-type, basic helix-loop-helix (bHLH) domain Neurogenic differentiation factor 2 Neurogenic differentiation factor, domain of unknown function Neurogenic differentiation factor NeuroD
UniProtKB:Q9W6C8 363
UniProtKB:B3DFQ6 363
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations