Gene

neurod2

ID

ZDB-GENE-010608-3

Name

neuronal differentiation 2

Symbol

neurod2 Nomenclature History

Previous Names

ndr2 (1)
fj49a11
NDF2 (1)
wu:fj49a11
zNdr2 (1)

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in neuron differentiation and regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in granule cell. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy. Orthologous to human NEUROD2 (neuronal differentiation 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

Thisse Expression Data

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With neurod2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
developmental and epileptic encephalopathy 72	Alliance	Developmental and epileptic encephalopathy 72	618374

Associated With neurod2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Domain	IPR022575	Neurogenic differentiation factor, domain of unknown function
Family	IPR016637	Neurogenic differentiation factor NeuroD
Family	IPR032649	Neurogenic differentiation factor 2
Homologous_superfamily	IPR036638	Helix-loop-helix DNA-binding domain superfamily